Purpose: The aim is to adapt the Cancer Information Overload Scale to Turkish and to establish its validity and reliability. Material and Methods: The study is a methodological one. The sample consists of 144 women aged between 18- 49 registered to a family health center between March-July 2015. The center is affiliated to the Denizli Provincial Health Center. The data were collected using the sociodemographic characteristics questionnaire, Cancer Information Overload, Scale Breast Cancer Health Belief Model. Language equivalence and content validity of the scale were established. Concurrent validity, Exploratory and confirmatory factor analysis was used to estimate the validity of the scale. Cronbach alpha and item-total correlations were measured to evaluate the reliability of the scale Results: In the exploratory factor analysis, the factor loadings were between 0.51-0.67, and the explained variance (38.35%) was considered sufficient. In the confirmatory factor analysis, the ratio of the postmodification of the chi square to the degrees of freedom was 2.04. Other compliance indices (RMSEA=0.085, GFI=0.94, AGFI=0.88, CFI=0.95, NFI=0.91, NNFI=0.92) were found to be at the desired level. In the reliability analysis, the internal consistency coefficient was α=0.77, which suggested that the scale was quite reliable, the item-total correlations of the scale varied between 0.38-0.52. Conclusion: It was determined that the validity and reliability of the Cancer Information Overload Scale was established and it could be used in the Turkish society.