The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate

KAYA, FILIZ; Canakci, Mustafa Emin; ozakin, engin; Struga, Genc; Yildirim, Huseyin; Acar, Nurdan; çevlik, rıdvan

doi:10.20515/otd.750745

The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate

Rıdvan Cevlik, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Engin Ozakin, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Huseyin Yildirim, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Eskişehir, Türkiye)

Esref Genc, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Nurdan Acar, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Filiz Baloglu Kaya, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Mustafa Emin Canakci (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Eskişehir, Türkiye)

Osmangazi Tıp Dergisi

6 1

Yıl: 2021 Cilt: 43 Sayı: 3 Sayfa Aralığı: 217 - 223 Metin Dili: İngilizce DOI: 10.20515/otd.750745 İndeks Tarihi: 14-05-2021

The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate

Öz:

Our study aimed to evaluate pleural lactate levels, to identify the reliability and validity of determining pleural fluid quality inpatients with pleural effusion.This is a prospective, observational study conducted on patients who were admitted to a universityhospital between July 1, 2017, and January 31, 2018, and diagnosed with pleural effusion. Pleural fluid classification into transudates and exudates was made according to Light’s criteria. The study group consisted of a total of 169 patients with pleural effusion,[99 (58.6%) male and aging 18-93 years (mean ± SD, 64.6 ± 16.1 years)]. Forty-four (26%) of the patients were evaluated as exudateand 125 (74%) as transudate. The median value of lactate was 3.20 mmol/L (min-max: 0.90-14.3) in exudate patients and 1.85mmol/L (min-max: 0.90-4.70) in transudate patients, and a significant difference was detected in the comparison of both (z: 5.894;p<0.001). There was a positive correlation between pleural lactate levels and pleural LDH, pleural LDH/serum LDH and pleuralprotein/serum protein ratios. The cut-off value of the pleural fluid lactate level was determined to be 2.0 for the highest sensitivityand specificity (sensitivity: 85%, specificity: 64%; AUC: 0.799). Measurement of lactate levels in pleural fluid can be useful for thedifferentiation of transudate and exudate fluid. Moreover, detection of lactate levels in a very short period may provide a moreuseful screening tool compared to other strategies.

Anahtar Kelime:

Transuda ve Eksüdayı Ayırt Etmek Için Plevral Laktat Ölçümünün Kullanılabilirliği

Öz:

Çalışmamız, plevral efüzyonlu hastalarda transüda ve eksüdayı ayırt etmenin güvenilirliğini ve geçerliliğini belirleyerek plevral laktat düzeylerini değerlendirmeyi amaçladı.1 Temmuz 2017 ile 31 Ocak 2018 tarihleri arasında bir üniversite hastanesine başvuran ve plevral efüzyon tanısı alan hastalar üzerinde yapılan prospektif, gözlemsel bir çalışmadır. Transüda ve eksüda plevral sıvı sınıflandırması Light kriterlerine göre yapılmıştır. Çalışma grubu pevral effüzyonlu toplam 169 hastadan oluştu [99 (% 58.6) erkek ve 18-93 yaş arası (ortalama ± SS, 64.6 ± 16.1 yıl)]. Hastaların 44’ü (% 26) eksüda ve 125’i transüda olarak değerlendirildi. Laktatın ortanca değeri eksüda hastalarda 3.20 mmol / L (min-maks: 0.90-14.3) ve transüda hastalarda 1.85 mmol / L (min-maks: 0.90-4.70) idi ve her ikisinin karşılaştırılmasında anlamlı farklılık saptandı. (z: 5.894; p <0.001). Plevral laktat seviyeleri ile plevral LDH, plevral LDH / serum LDH ve plevral protein / serum protein oranları arasında pozitif bir korelasyon tespit edildi. En yüksek duyarlılık ve özgüllük için plevral sıvı laktat düzeyinin kestirim değeri 2.0 olarak belirlendi (duyarlılık:% 85, özgüllük:% 64, AUC: 0.799). Plevral sıvıda laktat seviyelerinin ölçümü, transüda ve eksüda sıvısının ayrımı için yararlı olabilir. Ayrıca laktat seviyesinin çok kısa sürede tespiti diğer stratejilere göre daha kullanışlı bir tarama aracı olarak kullanılabilir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	çevlik r, ozakin e, Yildirim H, Struga G, Acar N, KAYA F, Canakci M (2021). The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. , 217 - 223. 10.20515/otd.750745
Chicago	çevlik rıdvan,ozakin engin,Yildirim Huseyin,Struga Genc,Acar Nurdan,KAYA FILIZ,Canakci Mustafa Emin The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. (2021): 217 - 223. 10.20515/otd.750745
MLA	çevlik rıdvan,ozakin engin,Yildirim Huseyin,Struga Genc,Acar Nurdan,KAYA FILIZ,Canakci Mustafa Emin The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. , 2021, ss.217 - 223. 10.20515/otd.750745
AMA	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. . 2021; 217 - 223. 10.20515/otd.750745
Vancouver	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. . 2021; 217 - 223. 10.20515/otd.750745
IEEE	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M "The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate." , ss.217 - 223, 2021. 10.20515/otd.750745
ISNAD	çevlik, rıdvan vd. "The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate". (2021), 217-223. https://doi.org/10.20515/otd.750745

APA	çevlik r, ozakin e, Yildirim H, Struga G, Acar N, KAYA F, Canakci M (2021). The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. Osmangazi Tıp Dergisi, 43(3), 217 - 223. 10.20515/otd.750745
Chicago	çevlik rıdvan,ozakin engin,Yildirim Huseyin,Struga Genc,Acar Nurdan,KAYA FILIZ,Canakci Mustafa Emin The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. Osmangazi Tıp Dergisi 43, no.3 (2021): 217 - 223. 10.20515/otd.750745
MLA	çevlik rıdvan,ozakin engin,Yildirim Huseyin,Struga Genc,Acar Nurdan,KAYA FILIZ,Canakci Mustafa Emin The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. Osmangazi Tıp Dergisi, vol.43, no.3, 2021, ss.217 - 223. 10.20515/otd.750745
AMA	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. Osmangazi Tıp Dergisi. 2021; 43(3): 217 - 223. 10.20515/otd.750745
Vancouver	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate. Osmangazi Tıp Dergisi. 2021; 43(3): 217 - 223. 10.20515/otd.750745
IEEE	çevlik r,ozakin e,Yildirim H,Struga G,Acar N,KAYA F,Canakci M "The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate." Osmangazi Tıp Dergisi, 43, ss.217 - 223, 2021. 10.20515/otd.750745
ISNAD	çevlik, rıdvan vd. "The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate". Osmangazi Tıp Dergisi 43/3 (2021), 217-223. https://doi.org/10.20515/otd.750745