Purpose: This study was planned to determine the efficacy of late-period physiotherapy for late-period biomechanical problems in foot-drop patients who underwent tibialis posterior tendon transfer after peripheral nerve injury. Methods: Twenty-two patients who were operated and followed up at least 6 months were included to the study. Demographic data and complications about patients were recorded and muscle force and ankle range-of-motion were evaluated. In addition, sense of joint position, balance, and quality of life were evaluated. In order to determine post-surgery success, Stanmore System Questionnaire was used. A physiotherapy program specifically based on individual patients’ needs included heat modalities, neuromuscular electrical stimulation, exercise, taping, and orthoses. Treatments were carried out 3 days a week, for the duration of 6 weeks. All pre-treatment evaluations were repeated in the 4th and 6th weeks and at the end of 3rd month to determine the effects of treatment. Results: During the study, muscle strength increased in ankle muscles of both affected and intact sides. In addition, proprioception, and balance improved. Quality-of-life was affected positively related with these changes. Conclusion: This study has revealed that late-period physical therapy practice in foot-drop patients who underwent tibialis posterior tendon transfer was effective on the late-period problems of the patients. This study has determined that the physiotherapy programs that are planned with detailed evaluation will improve patient satisfaction and surgical success.