Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic
Yıl: 2021 Cilt: 18 Sayı: 4 Sayfa Aralığı: 70 - 75 Metin Dili: İngilizce DOI: 10.4274/tjps.galenos.2020.88319 İndeks Tarihi: 17-01-2022
Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic
Öz: Objectives: This study aimed to evaluate the validity and reliability of an oral anticoagulation knowledge (OAK) test in Turkish patients on warfarin therapy at an anticoagulant outpatient clinic. Materials and Methods: This study was conducted at an ambulatory anticoagulation clinic and included patients older than 18 years who had been using warfarin for at least six months. Patients’ demographic and clinical data were collected. Internal consistency was calculated using the KuderRichardson 20 (KR-20) coefficient, and the test-retest reliability of the Turkish version of the OAK test was assessed. Results: Patients’ mean age was 59.83±11.93 (26-90) years (n=240; 133 women). The mean score of the OAK test was 14.19±3.01. The test-retest reliability of the scale (n=30) was moderate for the total score (p<0.001). The KR-20 value, a measure of internal consistency, was 0.671. Patients of a younger age and higher educational level were more likely to have higher levels of anticoagulation knowledge than patients of an older age and lower education level (p<0.05 for both comparisons). Conclusion: The Turkish version of the OAK test can be used to determine the patients’ knowledge on oral anticoagulation.
Anahtar Kelime: Ayaktan Antikoagülasyon Kliniğinde Varfarin Tedavisi Alan Türk Hastalarında Bir Bilgi Testinin Validasyonu
Öz: Amaç: Bu çalışmada, bir antikoagülan polikliniğinde varfarin tedavisi alan Türk hastalarda oral antikoagülasyon bilgisi (OAK) testinin geçerlilik ve güvenilirliğinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Bu çalışma ayaktan antikoagülasyon kliniğinde yürütülmüştür ve en az altı aydır varfarin kullanan 18 yaşından büyük hastaları kapsamaktadır. Hastaların demografik ve klinik verileri toplanmıştır. Kuder-Richardson 20 (KR-20) katsayısı kullanılarak iç tutarlılık hesaplanmış ve OAK testinin Türkçe versiyonunun test-tekrar test güvenilirliği değerlendirilmiştir. Bulgular: İki yüz kırk hastanın (133 kadın) yaş ortalaması 59,83±11,93 (26-90) idi. Oral antikoagülasyon bilgi testinin ortalama skoru 14,19±3,01 olarak hesaplanmıştır. Ölçeğin test-tekrar test güvenirliği (n=30) toplam skor için orta düzeyde bulunmuştur (p<0,001). İç tutarlılık güvenirliği, hesaplanan KR-20 değeri (0,671) ile doğrulanmıştır. Daha genç ve yüksek eğitim düzeyindeki hastalar, daha ileri yaşta ve düşük eğitim düzeyindeki hastalarla karşılaştırıldığında daha yüksek antikoagülasyon bilgisine sahip olarak belirlenmiştir (her iki karşılaştırma için p<0,05). Sonuç: Hastaların oral antikoagülasyon konusundaki bilgilerini belirlemek için OAK testinin Türkçe versiyonu kullanılabilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- da Silva Praxedes MF, de Abreu MHNG, Paiva SM, de Melo Mambrini JV, Marcolino MS, Martins MAP. Assessment of psychometric properties of the Brazilian version of the oral anticoagulation knowledge test. Health Qual Life Outcomes. 2016;14:96.
- Joshua JK, Kakkar N. Lacunae in patient knowledge about oral anticoagulant treatment: results of a questionnaire survey. Indian J Hematol Blood Transfus. 2015;31:275-280.
- Dumas S, Rouleau-Maillous E, Bouchama N, Lahcene H, Talajic M, Tardif JC, Gualin MJ, Provost S, Dubé MP, Perreault S. Pillbox use and INR stability in a prospective cohort of new warfarin users. J Manag Care Spec Pharm. 2016;22:676-684.
- Gallagher J, Mc Carthy S, Woods N, Ryan F, O’Shea S, Byrne S. Economic evaluation of a randomized controlled trial of pharmacist-supervized patient self-testing of warfarin therapy. J Clin Pharm Ther. 2015;40:14- 19.
- de Terline MD, Hejblum G, Fernandez C, Cohen A, Antignac M. Discrepancies between patients’ preferences and educational programs on oral anticoagulant therapy: a survey in community pharmacies and hospital consultations. PloS One. 2016;11:e0146927.
- Barnes GD, Nallamothu BK, Sales AE, Froehlich JB. Reimagining anticoagulation clinics in the era of direct oral anticoagulants. Circ Cardiovasc Qual Outcomes. 2016;9:182-185.
- Kimmel SE, Troxel AB, French B, Loewenstein G, Doshi JA, Hecht TE, Laskin M, Brensinger CM, Meussner C, Volpp K. A randomized trial of lottery-based incentives and reminders to improve warfarin adherence: the warfarin incentives (WIN2) trial. Pharmacoepidemiol Drug Saf. 2016;25:1219-1227.
- Wang Y, Kong MC, Lee LH, Ng HJ, Ko Y. Knowledge, satisfaction, and concerns regarding warfarin therapy and their association with warfarin adherence and anticoagulation control. Thromb Res. 2014;133:550-554.
- Baykız D, Akyuz A, Alpsoy S, Fidan C. The influence of warfarin adherence on time in therapeutic range among patients with mechanical heart valves. J Heart Valve Dis. 2018;27:55-64.
- Çelik A, İzci S, Kobat MA, Ateş AH, Çakmak A, Çakıllı Y, Yılmaz MB, Zoghi M. The awareness, efficacy, safety, and time in therapeutic range of warfarin in the Turkish population: WARFARIN-TR. Anatol J Cardiol. 2016;16:595.
- Briggs AL, Jackson TR, Bruce S, Shapiro NL. The development and performance validation of a tool to assess patient anticoagulation knowledge. Res Social Adm Pharm. 2005;1:40-59.
- Obamiro KO, Chalmers L, Bereznicki LR. Development and validation of an oral anticoagulation knowledge tool (AKT). PloS One. 2016;11:e0158071.
- Shilbayeh SAR, Almutairi WA, Alyahya SA, Alshammari NH, Shaheen E, Adam A. Validation of knowledge and adherence assessment tools among patients on warfarin therapy in a Saudi hospital anticoagulant clinic. Int J Clin Pharm. 2018;40:56-66.
- Zeolla MM, Brodeur MR, Dominelli A, Haines ST, Allie ND. Development and validation of an instrument to determine patient knowledge: the oral anticoagulation knowledge test. Ann Pharmacother. 2006;40:633-638.
- Matalqah L, Radaideh K, Sulaiman S, Hassali MA, Abdul Kader MAS. Relationship between patients’ warfarin knowledge and anticoagulation control: results of a validated tool in Malaysia. J Pharm Biomed Sci. 2013;30:967-974.
- Streiner DL, Norman GR, Cairney J, Health measurement scales: a practical guide to their development and use. 3rd ed. New York; Oxford University Press; 2003.
- Rosendaal F, Cannegieter S, Van der Meer F, Briet E. A method to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost. 1993;70:236-239.
- Alphonsa A, Sharma KK, Sharma G, Bhatia R. Knowledge regarding oral anticoagulation therapy among patients with stroke and those at high risk of thromboembolic events. J Stroke Cerebrovasc Dis. 2015;24:668- 672.
- Nybo M, Skov J. Patient knowledge of anticoagulant treatment does not correlate with treatment quality. Public Health. 2016;141:17-22.
- Hu A, Chow CM, Dao D, Errett L, Keith M. Factors influencing patient knowledge of warfarin therapy after mechanical heart valve replacement. J Cardiovasc Nurs. 2006;21:169-175.
- Al-Omair SF, Musallam NA, Al-Deghaither NY, Al-Sadoun NA, Bayoumy NM. Compliance with and awareness about long-term oral anticoagulant therapy among Saudi patients in a University Hospital Riyadh, Saudi Arabia. J Appl Hematol. 2016,7;10.
- Elbur AI, Albarraq A, Maugrabi M, Alharthi S. Knowledge of, satisfaction with and adherence to oral anticoagulant drugs among patients in King Fasial Hospital: Taif, Kingdom Saudi Arabia. Int J Pharm Sci Res. 2015;31:274-280.
- Mayet AY. Association between oral anticoagulation knowledge, anticoagulation control, and demographic characteristics of patients attending an anticoagulation clinic in Saudi Arabia: A cross-sectional prospective evaluation. Trop J Pharm Res. 2015;14:1285-1291.
- Davis NJ, Billett HH, Cohen HW, Arnsten JH. Impact of adherence, knowledge, and quality of life on anticoagulation control. Ann Pharmacother. 2005;39:632-636.
- Tang EOY, Lai CS, Lee KK, Wong RS, Cheng G, Chan TY. Relationship between patients’ warfarin knowledge and anticoagulation control. Ann Pharmacother. 2003;7:34-39.
- Khudair I, Hanssens Y. Evaluation of patients’ knowledge on warfarin in outpatient anticoagluant clinics in a teaching hosiptal in Qatar. Saudi Med J. 2010;31:672-677.
- Barcellona D, Contu P, Marongiu F. Patient education and oral anticoagulant therapy. Haematologica. 2002;87:1081-1086.
- Ryals CA, Pierce KL, Baker JW. INR goal attainment and oral anticoagulation knowledge of patients enrolled in an anticoagulation clinic in a Veterans Affairs medical center. J Manag Care Pharm. 2011;17:133-142.
- Li X, Sun S, Wang Q, Chen B, Zhao Z, Xu X. Assessment of patients’ warfarin knowledge and anticoagulation control at a joint physicianand pharmacist-managed clinic in China. Patient Prefer Adherence. 2018;12:783.
| APA | Turker M, SANCAR M, Demirtunc R, Uçar-Yaman N, Uzman O, AY N, Kozan O, Okuyan B (2021). Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. , 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| Chicago | Turker Meltem,SANCAR MESUT,Demirtunc Refik,Uçar-Yaman Nazlıcan,Uzman Osman,AY NADIYE PINAR,Kozan Omer,Okuyan Betul Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. (2021): 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| MLA | Turker Meltem,SANCAR MESUT,Demirtunc Refik,Uçar-Yaman Nazlıcan,Uzman Osman,AY NADIYE PINAR,Kozan Omer,Okuyan Betul Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. , 2021, ss.70 - 75. 10.4274/tjps.galenos.2020.88319 |
| AMA | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. . 2021; 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| Vancouver | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. . 2021; 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| IEEE | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B "Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic." , ss.70 - 75, 2021. 10.4274/tjps.galenos.2020.88319 |
| ISNAD | Turker, Meltem vd. "Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic". (2021), 70-75. https://doi.org/10.4274/tjps.galenos.2020.88319 |
| APA | Turker M, SANCAR M, Demirtunc R, Uçar-Yaman N, Uzman O, AY N, Kozan O, Okuyan B (2021). Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. Turkish Journal of Pharmaceutical Sciences, 18(4), 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| Chicago | Turker Meltem,SANCAR MESUT,Demirtunc Refik,Uçar-Yaman Nazlıcan,Uzman Osman,AY NADIYE PINAR,Kozan Omer,Okuyan Betul Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. Turkish Journal of Pharmaceutical Sciences 18, no.4 (2021): 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| MLA | Turker Meltem,SANCAR MESUT,Demirtunc Refik,Uçar-Yaman Nazlıcan,Uzman Osman,AY NADIYE PINAR,Kozan Omer,Okuyan Betul Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. Turkish Journal of Pharmaceutical Sciences, vol.18, no.4, 2021, ss.70 - 75. 10.4274/tjps.galenos.2020.88319 |
| AMA | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. Turkish Journal of Pharmaceutical Sciences. 2021; 18(4): 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| Vancouver | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic. Turkish Journal of Pharmaceutical Sciences. 2021; 18(4): 70 - 75. 10.4274/tjps.galenos.2020.88319 |
| IEEE | Turker M,SANCAR M,Demirtunc R,Uçar-Yaman N,Uzman O,AY N,Kozan O,Okuyan B "Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic." Turkish Journal of Pharmaceutical Sciences, 18, ss.70 - 75, 2021. 10.4274/tjps.galenos.2020.88319 |
| ISNAD | Turker, Meltem vd. "Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic". Turkish Journal of Pharmaceutical Sciences 18/4 (2021), 70-75. https://doi.org/10.4274/tjps.galenos.2020.88319 |
