This study aims to identify knowledge and attitudes towards traditional and complementary medicine interventions in individuals presenting to physical therapy and outpatient clinic. This is a cross-sectional study. The study was approved by Yozgat Bozok University Ethics Committee on Clinical Research. The data were collected using a questionnaire. Data were collected using a questionnaire through face-to-face interview method. Overall, 550 individuals aged ≥18 years were recruited at the end of study. Of participants, 83.5% reported that they could use traditional and complementary medical interventions for treatment of a health problem while 35.5% reported that they previously used these interventions in a health problem, 95.4% of those who reported that they would continue to use the intervention. The cupping and leech therapy were the most common interventions. The participants often reported that they preferred traditional and comple- mentary medicine as they thought that these interventions were natural and safe with less adverse effect and they believe that these interventions will improve their quality of life. Participants defined these interventions as those which make them feel better. It is important to provide better counseling regarding potential risk, benefits and limitations of traditional and complementary medicine interventions which are increasingly used in Turkey and worldwide and to guide community through provision of these interventions by clinicians.