Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens

Durak, Haydar; özgen, mahir bülent; Dincer, Alp; Türkeri, Levent; Özveren, Bora; Karsiyakali, Nejdet; Akbal, Cem

doi:10.4274/uob.galenos.2020.1874

Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens

Nejdet Karşıyakalı, (Acıbadem Mehmet Ali Aydınlar University, Altunizade Hospital, Clinic of Urology, İstanbul,Türkiye)

Levent TÜRKERİ, (Acıbadem Mehmet Ali Aydınlar University, Altunizade Hospital, Clinic of Urology, İstanbul,Türkiye)

Bora Özveren, (Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Altunizade Hospital, Clinic of Urology, İstanbul, Türkiye)

Cem Akbal, (Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Altunizade Hospital, Clinic of Urology, İstanbul, Türkiye)

Alp Dinçer, (Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Altunizade Hospital, Clinic of Radiology, İstanbul, Türkiye)

Haydar Durak, (Acıbadem Mehmet Ali Aydınlar University, Altunizade Hospital, Clinic of Clinical Pathology Laboratory, İstanbul, Türkiye)

Mahir Bülent ÖZGEN (Acıbadem Mehmet Ali Aydınlar University, Altunizade Hospital, Clinic of Urology, İstanbul,Türkiye)

Üroonkoloji Bülteni

1 0

Yıl: 2021 Cilt: 20 Sayı: 3 Sayfa Aralığı: 147 - 152 Metin Dili: İngilizce DOI: 10.4274/uob.galenos.2020.1874 İndeks Tarihi: 19-05-2022

Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens

Öz:

Objective: This study aimed to investigate the correlation between index lesion prostate imaging-reporting and data system (PI-RADS) version-2 score and histopathological outcomes of prostatectomy specimens. Materials and Methods: A total of 78 male patients with prostate cancer (PCa) treated with robot-assisted radical prostatectomy between August 2015 and June 2020 were included in this study. In this cohort, suspicious lesions on multiparametric magnetic resonance imaging (mpMRI) were scored according to PI-RADS version-2 criteria. MpMRI-targeted prostate biopsy was performed for all suspicious lesions with a PI-RADS score of ≥3 followed by systematic prostate biopsy. The relationship between index lesion PI-RADS score and histopathological outcomes of prostatectomy specimens were evaluated statistically. Results: The mean age of the patients was 65.0±7.0 years. The distribution of PI-RADS scores of 3, 4, and 5 of the index lesions were 6 (7.7%), 29 (37.2%), and 43 (55.1%), respectively. Lower tumor volume and tumor volume ratio were observed in patients with a PI-RADS score of 3 when they were compared with patients with PI-RADS scores of 4 and PI-RADS-5 (p<0.001, for each). No significant correlation was found between index lesion PI-RADS score in mpMRI and clinically significant PCa in prostatectomy specimens (r<0.200, p>0.05). However, a significant correlation was observed between index lesion PI-RADS score and extracapsular extension (ECE), as well as seminal vesicle invasion (SVI) and pT stage (r=0.327, p=0.004; r=0.276, p=0.014, r=0.348, p=0.002, respectively). Conclusion: Increased index lesion PI-RADS scores were associated with ECE, SVI, higher tumor volume, tumor volume ratio, and pT stages. Increased index lesion PI-RADS score in mpMRI may be helpful in prediction of locally advanced PCa in prostatectomy specimens.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Karsiyakali N, Türkeri L, Özveren B, Akbal C, Dincer A, Durak H, özgen m (2021). Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. , 147 - 152. 10.4274/uob.galenos.2020.1874
Chicago	Karsiyakali Nejdet,Türkeri Levent,Özveren Bora,Akbal Cem,Dincer Alp,Durak Haydar,özgen mahir bülent Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. (2021): 147 - 152. 10.4274/uob.galenos.2020.1874
MLA	Karsiyakali Nejdet,Türkeri Levent,Özveren Bora,Akbal Cem,Dincer Alp,Durak Haydar,özgen mahir bülent Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. , 2021, ss.147 - 152. 10.4274/uob.galenos.2020.1874
AMA	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. . 2021; 147 - 152. 10.4274/uob.galenos.2020.1874
Vancouver	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. . 2021; 147 - 152. 10.4274/uob.galenos.2020.1874
IEEE	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m "Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens." , ss.147 - 152, 2021. 10.4274/uob.galenos.2020.1874
ISNAD	Karsiyakali, Nejdet vd. "Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens". (2021), 147-152. https://doi.org/10.4274/uob.galenos.2020.1874

APA	Karsiyakali N, Türkeri L, Özveren B, Akbal C, Dincer A, Durak H, özgen m (2021). Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. Üroonkoloji Bülteni, 20(3), 147 - 152. 10.4274/uob.galenos.2020.1874
Chicago	Karsiyakali Nejdet,Türkeri Levent,Özveren Bora,Akbal Cem,Dincer Alp,Durak Haydar,özgen mahir bülent Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. Üroonkoloji Bülteni 20, no.3 (2021): 147 - 152. 10.4274/uob.galenos.2020.1874
MLA	Karsiyakali Nejdet,Türkeri Levent,Özveren Bora,Akbal Cem,Dincer Alp,Durak Haydar,özgen mahir bülent Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. Üroonkoloji Bülteni, vol.20, no.3, 2021, ss.147 - 152. 10.4274/uob.galenos.2020.1874
AMA	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. Üroonkoloji Bülteni. 2021; 20(3): 147 - 152. 10.4274/uob.galenos.2020.1874
Vancouver	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens. Üroonkoloji Bülteni. 2021; 20(3): 147 - 152. 10.4274/uob.galenos.2020.1874
IEEE	Karsiyakali N,Türkeri L,Özveren B,Akbal C,Dincer A,Durak H,özgen m "Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens." Üroonkoloji Bülteni, 20, ss.147 - 152, 2021. 10.4274/uob.galenos.2020.1874
ISNAD	Karsiyakali, Nejdet vd. "Increased Prostate Imaging-Reporting and Data System Scores in Multiparametric Magnetic Resonance Imaging May Predict More Extensive Disease in Radical Prostatectomy Specimens". Üroonkoloji Bülteni 20/3 (2021), 147-152. https://doi.org/10.4274/uob.galenos.2020.1874