Yıl: 2020 Cilt: 58 Sayı: 2 Sayfa Aralığı: 93 - 98 Metin Dili: İngilizce DOI: 10.5152/tao.2020.5276 İndeks Tarihi: 02-06-2022

Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies

Öz:
Objective: The aim of this study is to share our surgical approach and results in patients with benign and malignant thyroid diseases. Methods: All patients who underwent thyroid gland surgery at our University Hospital Ear, Nose, and Throat Department between 2012 and 2017 were retrospectively analyzed. The study included 293 patients. Results: Of the 293 patients included in the study, 76 (25.9%) were male and 217 (74.1%) were female. Mean follow-up period was 47.1 months. Patients’ ages ranged from 4 to 77 years. In terms of the pathology, 160 patients had benign and 133 had neoplastic thyroid diseases. None of the patients who underwent thyroid surgery due to benign diseases required revision surgery. Recurrence occurred in 15 out of the 116 patients that were operated on for well-differentiated thyroid cancer. Out of these 15 patients with disease recurrence, 11 had biochemically incomplete responses and four had structurally recurrent diseases. Conclusion: Thyroidectomy, when performed safely and correctly, is a very effective way of treating both benign and malignant thyroid diseases. Total thyroidectomy or total lobectomy and isthmectomy are the gold-standard surgical approaches to prevent recurrence. A national form is needed regarding thyroid surgery for following up on patients and for the regular and systematic collection of data.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Röjdmark J, Järhult J. High long term recurrence rate after subtotal thyroidectomy for nodular goitre. EurJ Surg 1995; 161: 725-7.
  • 2. Patel UA. Surgical treatment of thyroid disease. In: Washington Manual Otolaryngology Survival Guide. Lippincott Williams & Wilkins, 2003.
  • 3. Pellegriti G, Frasca F, Regalbuto C, Squatrito S, Vigneri R. Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors. J Cancer Epidemiol 2013; 2013: 965212. [Crossref]
  • 4. Rahbari R, Zhang L, Kebebew E. Thyroid cancer gender disparity. Future Oncol 2010; 6: 1771-9. [Crossref]
  • 5. Malchoff CD, Malchoff DM. Familial nonmedullary thyroid carcinoma. Cancer Control. 2006;13:106-10. [Crossref]
  • 6. Hundahl SA, Fleming ID, Fremgen AM, Menck HR. A national cancer data base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985‐1995. Cancer 1998; 83: 2638-48. [Crossref]
  • 7. Hundahl SA, Cady B, Cunningham MP, Mazzaferri E, McKee RF, Rosai J, et al. Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the United States during 1996: an American college of surgeons commission on cancer patient care evaluation study. Cancer 2000; 89: 202-17. [Crossref]
  • 8. Rosai J, Carangui ML, DeLellis RA. Atlas of tumor pathology: tumors of the thyroid gland. Washington, DC: Armed Forces Institute of Pathology; 1992.
  • 9. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016; 26: 1-133. [Crossref]
  • 10. Bongiovanni M, Spitale A, Faquin WC, Mazzucchelli L, Baloch ZW. The Bethesda system for reporting thyroid cytopathology: a meta-analysis. Acta Cytol 2012; 56: 333-9. [Crossref]
  • 11. Paksoy M, Aydın S, Ayduran E, Eken M, Şanlı A, Taşdemir Ö. Tiroid kitlelerinde klinik bulgular ve uyguladığımız tedavi yöntemleri. Kulak Burun Boğaz İhtis Derg 2008; 18: 294-9.
  • 12. McIver B, Hay ID, Giuffrida DF, Dvorak CE, Grant CS, Thompson GB, et al. Anaplastic thyroid carcinoma: a 50-year experience at a single institution. Surgery 2001; 130: 1028-34. [Crossref]
  • 13. Chen J, Tward JD, Shrieve DC, Hitchcock YJ. Surgery and radiotherapy improves survival in patients with anaplastic thyroid carcinoma: analysis of the surveillance, epidemiology, and end results 1983–2002. Am J Clin Oncol 2008; 31: 460-4. [Crossref]
  • 14. Smallridge RC, Ain KB, Asa SL, Bible KC, Brierley JD, Burman KD, et al. American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer. Thyroid 2012; 22: 1104-39. [Crossref]
APA Yumusakhuylu A, asya o, GUNDOGDU y, OYSU C (2020). Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. , 93 - 98. 10.5152/tao.2020.5276
Chicago Yumusakhuylu Ali,asya orhan,GUNDOGDU yavuz,OYSU CAGATAY Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. (2020): 93 - 98. 10.5152/tao.2020.5276
MLA Yumusakhuylu Ali,asya orhan,GUNDOGDU yavuz,OYSU CAGATAY Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. , 2020, ss.93 - 98. 10.5152/tao.2020.5276
AMA Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. . 2020; 93 - 98. 10.5152/tao.2020.5276
Vancouver Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. . 2020; 93 - 98. 10.5152/tao.2020.5276
IEEE Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C "Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies." , ss.93 - 98, 2020. 10.5152/tao.2020.5276
ISNAD Yumusakhuylu, Ali vd. "Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies". (2020), 93-98. https://doi.org/10.5152/tao.2020.5276
APA Yumusakhuylu A, asya o, GUNDOGDU y, OYSU C (2020). Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. Turkish archives of otorhinolaryngology , 58(2), 93 - 98. 10.5152/tao.2020.5276
Chicago Yumusakhuylu Ali,asya orhan,GUNDOGDU yavuz,OYSU CAGATAY Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. Turkish archives of otorhinolaryngology 58, no.2 (2020): 93 - 98. 10.5152/tao.2020.5276
MLA Yumusakhuylu Ali,asya orhan,GUNDOGDU yavuz,OYSU CAGATAY Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. Turkish archives of otorhinolaryngology , vol.58, no.2, 2020, ss.93 - 98. 10.5152/tao.2020.5276
AMA Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. Turkish archives of otorhinolaryngology . 2020; 58(2): 93 - 98. 10.5152/tao.2020.5276
Vancouver Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies. Turkish archives of otorhinolaryngology . 2020; 58(2): 93 - 98. 10.5152/tao.2020.5276
IEEE Yumusakhuylu A,asya o,GUNDOGDU y,OYSU C "Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies." Turkish archives of otorhinolaryngology , 58, ss.93 - 98, 2020. 10.5152/tao.2020.5276
ISNAD Yumusakhuylu, Ali vd. "Clinicopathologic Results of the Surgical Management of Thyroid Gland Pathologies". Turkish archives of otorhinolaryngology 58/2 (2020), 93-98. https://doi.org/10.5152/tao.2020.5276