Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward
Yıl: 2022 Cilt: 26 Sayı: 3 Sayfa Aralığı: 669 - 678 Metin Dili: İngilizce DOI: 10.29228/jrp.166 İndeks Tarihi: 08-06-2022
Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward
Öz: Integrating clinical pharmacists in a multidisciplinary patient care team improves the treatment process
by identifying and resolving drug-related problems (DRPs). The aim of the study was to determine the effect of clinical
pharmacist intervention for DRPs in the gastroenterology service. The first period of the study was conducted between
15.06.2018 and 15.02.2019. Eighty patients admitted to the gastroenterology ward, who used at least one medication,
were included in ‘the study group’. The clinical pharmacist participated in ward rounds and made interventions to
solve identified DRPs. In the second period of the study, the control group consisted of 80 patients admitted to the same
ward between 01.03.2019 and 06.06.2019. DRPs were determined only from the data obtained from the hospital system
in the control group. DRPs were classified according to the European Pharmaceutical Care Network (PCNE V9.1). A
total of 136 and 46 with an average of 1.7 and 0.57 DRPs per patient (p≤0.01) were identified in the study and control
groups, respectively. Of the DRPs in the study group, 59 were related to treatment effectiveness, while 61 were related
to treatment safety. Likewise, 21 DRPs were related to treatment effectiveness in the control group, while 12 were related
to treatment (p≤0.01). 65% of the interventions were made at the physician level and 49% at the drug level. 97% (n=133)
of the total interventions were accepted. The number of DRPs was significantly reduced in the control group within the
time frame after the clinical pharmacist intervention period. In conclusion, clinical pharmacists' importance in detecting
and preventing DRPs in the gastroenterology ward has been demonstrated.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- [1] Viktil KK, Blix HS. The impact of clinical pharmacists on drug-related problems and clinical outcomes. Basic Clin Pharmacol Toxicol. 2008;102(3):275-280. [CrossRef]
- [2] https://www.pcne.org/ Pharmaceutical Care Network Europe (PCNE). https://www.pcne.org/ (Accessed date: 03.01.2021).
- [3] Naples JG, Hanlon JT, Schmader KE, Semla TP. Recent Literature on Medication Errors and Adverse Drug Events in Older Adults. J Am Geriatr Soc. 2016;64(2):401-408. [CrossRef]
- [4] Salvi F, Marchetti A, D'Angelo F, Boemi M, Lattanzio F, Cherubini A. Adverse Drug Events as a Cause of Hospitalization in Older Adults. Drug Saf 35, 29–45 (2012). [CrossRef]
- [5] Gleason KM, McDaniel MR, Feinglass J, et al. Results of the Medications at Transitions and Clinical Handoffs (MATCH) study: an analysis of medication reconciliation errors and risk factors at hospital admission. J Gen Intern Med. 2010;25(5):441-447. [CrossRef]
- [6] Unroe KT, Pfeiffenberger T, Riegelhaupt S, Jastrzembski J, Lokhnygina Y, Colón-Emeric C. Inpatient medication reconciliation at admission and discharge: A retrospective cohort study of age and other risk factors for medication discrepancies. Am J Geriatr Pharmacotherapy. 2010;8(2):115-126. [CrossRef]
- [7] Reis WC, Scopel CT, Correr CJ, Andrzejevski VM. Analysis of clinical pharmacist interventions in a tertiary teaching hospital in Brazil. Einstein (Sao Paulo). 2013;11(2):190-196. [CrossRef]
- [8] Pippins JR, Gandhi TK, Hamann C, et al. Classifying and predicting errors of inpatient medication reconciliation. J Gen Intern Med. 2008;23(9):1414-1422. [CrossRef]
- [9] Bedouch P, Sylvoz N, Charpiat B, et al. Trends in pharmacists' medication order review in French hospitals from 2006 to 2009: analysis of pharmacists' interventions from the Act-IP© website observatory. J Clin Pharm Ther. 2015;40(1):32-40. [CrossRef]
- [10] Blix HS, Viktil KK, Moger TA, Reikvam A. Characteristics of drug-related problems discussed by hospital pharmacists in multidisciplinary teams. Pharm World Sci. 2006;28(3):152-158. [CrossRef]
- [11] Delgado Silveira E, Fernandez-Villalba EM, García-Mina Freire M, Albiñana Pérez MS, Casajús Lagranja MP, Peris Martí JF. Impacto de la Intervención Farmacéutica en el tratamientodel paciente mayor pluripatológico [The impact of Pharmacy Intervention on the treatment of elderly multi-pathological patients]. Farm Hosp. 2015;39(4):192-202. Published 2015 Jul 1. [CrossRef]
- [12] Babelghaith SD, Wajid S, Alrabiah Z, et al. Drug-Related Problems and Pharmacist Intervention at a General Hospital in the Jazan Region, Saudi Arabia. Risk Manag Healthc Policy. 2020;13:373-378. [CrossRef]
- [13] Hailu BY, Berhe DF, Gudina EK, Gidey K, Getachew M. Drug related problems in admitted geriatric patients: the impact of clinical pharmacist interventions. BMC Geriatr. 2020;20(1):13. [CrossRef]
- [14] Kara E, Kelleci Çakır B, Sancar M, Demirkan K. Impact of Clinical Pharmacist-led Interventions in Turkey. Turk J Pharm Sci. 2021;18(4):517-526. [CrossRef]
- [15] Lenssen R, Heidenreich A, Schulz JB, et al. Analysis of drug-related problems in three departments of a German University hospital. Int J Clin Pharm. 2016;38(1):119-126. [CrossRef]
- [15] Niquille A, Bugnon O. Relationship between drug-related problems and health outcomes: A crosssectional study among cardiovascular patients. Pharm World Sci. 2010;32(4):512–9. [CrossRef]
- [16] Abunahlah N, Elawaisi A, Velibeyoglu FM, Sancar M. Drug related problems identified by clinical pharmacist at the Internal Medicine Ward in Turkey. Int J Clin Pharm. 2018;40(2):360-367. [CrossRef]
- [17] Movva R, Jampani A, Nathani J, Pinnamaneni S, Challa S. A prospective study of incidence of medicationrelated problems in general medicine ward of a tertiary care hospital. J Adv Pharm Technol Res. 2015;6(4):190– 4. [CrossRef]
- [18] Lenssen R, Heidenreich A, Schulz JB, et al. Analysis of drug-related problems in three departments of a German University hospital. Int J Clin Pharm. 2016;38(1):119-126. [CrossRef]
- [19] Saldanha V, Randall Martins R, Lima SIVC, Batista de Araujo I, Gouveia Oliveira A. Incidence, types and acceptability of pharmaceutical interventions about drug related problems in a general hospital: an open prospective cohort. BMJ Open. 2020;10(4):e035848. [CrossRef]
- [20] Al-Azzam SI, Alzoubi KH, Aburuz S, Alefan Q. Drug-related problems in a sample of outpatients with chronic diseases: A cross-sectional study from Jordan. Ther Clin Risk Manag. 2016;12:233–9. [CrossRef]
- [21] Madhu GS, James E, Venu RP. Appropriateness of antibiotic usage for gastrointestinal disorders in a tertiary care hospital. Eur J Hosp Pharm . 2016;23(5):283–7. [CrossRef]
- [22] Liu XX, Wang HX, Hu YY, Zhu XT, Tan X, Yang Y, et al. Drug-related problems identified by clinical pharmacists in nephrology department of a tertiary hospital in china—a single center study. Ann Palliat Med. 2021;10(8):8701–8. [CrossRef]
- [23] Perlman A, Horwitz E, Hirsh-Raccah B, Aldouby-Bier G, Fisher Negev T, Hochberg-Klein S, et al. Clinical pharmacist led hospital-wide direct oral anticoagulant stewardship program. Isr J Health Policy Res. 2019;8(1):1–9. [CrossRef]
- [24] Hayward KL, Patel PJ, Valery PC, Horsfall LU, Li CY, Wright PL, et al. Medication-Related Problems in Outpatients With Decompensated Cirrhosis: Opportunities for Harm Prevention. Hepatol Commun. 2019;3(5):620–31. [CrossRef]
- [25] Masnoon N, Shakib S, Kalisch-Ellett L, Caughey
| APA | CEYLAN C, SANCAR M, BECEREN A, DEMİR A, KUŞ C, OMURTAG G (2022). Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. , 669 - 678. 10.29228/jrp.166 |
| Chicago | CEYLAN Cengizhan,SANCAR MESUT,BECEREN Ayfer,DEMİR ALİ,KUŞ COŞKUN,OMURTAG Gülden Zehra Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. (2022): 669 - 678. 10.29228/jrp.166 |
| MLA | CEYLAN Cengizhan,SANCAR MESUT,BECEREN Ayfer,DEMİR ALİ,KUŞ COŞKUN,OMURTAG Gülden Zehra Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. , 2022, ss.669 - 678. 10.29228/jrp.166 |
| AMA | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. . 2022; 669 - 678. 10.29228/jrp.166 |
| Vancouver | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. . 2022; 669 - 678. 10.29228/jrp.166 |
| IEEE | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G "Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward." , ss.669 - 678, 2022. 10.29228/jrp.166 |
| ISNAD | CEYLAN, Cengizhan vd. "Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward". (2022), 669-678. https://doi.org/10.29228/jrp.166 |
| APA | CEYLAN C, SANCAR M, BECEREN A, DEMİR A, KUŞ C, OMURTAG G (2022). Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. Journal of research in pharmacy (online), 26(3), 669 - 678. 10.29228/jrp.166 |
| Chicago | CEYLAN Cengizhan,SANCAR MESUT,BECEREN Ayfer,DEMİR ALİ,KUŞ COŞKUN,OMURTAG Gülden Zehra Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. Journal of research in pharmacy (online) 26, no.3 (2022): 669 - 678. 10.29228/jrp.166 |
| MLA | CEYLAN Cengizhan,SANCAR MESUT,BECEREN Ayfer,DEMİR ALİ,KUŞ COŞKUN,OMURTAG Gülden Zehra Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. Journal of research in pharmacy (online), vol.26, no.3, 2022, ss.669 - 678. 10.29228/jrp.166 |
| AMA | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. Journal of research in pharmacy (online). 2022; 26(3): 669 - 678. 10.29228/jrp.166 |
| Vancouver | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward. Journal of research in pharmacy (online). 2022; 26(3): 669 - 678. 10.29228/jrp.166 |
| IEEE | CEYLAN C,SANCAR M,BECEREN A,DEMİR A,KUŞ C,OMURTAG G "Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward." Journal of research in pharmacy (online), 26, ss.669 - 678, 2022. 10.29228/jrp.166 |
| ISNAD | CEYLAN, Cengizhan vd. "Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward". Journal of research in pharmacy (online) 26/3 (2022), 669-678. https://doi.org/10.29228/jrp.166 |
