Yıl: 2021 Cilt: 4 Sayı: 4 Sayfa Aralığı: 130 - 132 Metin Dili: İngilizce DOI: 10.47115/bsagriculture.988347 İndeks Tarihi: 29-07-2022

Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep

Öz:
In the early 1980s, by the determination of the Boorola gene (FecB) in Booroola sheep with high ovulation rate, there has been a great interest for identification of genes that are responsible for prolificacy and their use in breeding programs.The mutation occurred in Bone morphogenetic protein 15 (BMP15), Bone morphogenetic protein-1B (BMPR-1B) and Growth differentiation factor 9 (GDF9) genes have been found to increase the ovulation rate. Additionally some others gene are known to exist based on expressed inheritance patterns although the location of mutations has yet to be found. In the BMP15 gene, with almost the same phenotypic expression eight distinct mutations have been recognized, among themHanna (FecXH) andInverdale (FecXI) were identified first in Romney sheep in New Zealand. X-linked dominant genes with sterility in homozygous females are the modes of inheritance of the BMP15 gene. A total of 88 prolific Awassi sheep were screened for the presence of the FecXI mutation in the BMP15 gene and FecXI mutation was not found in any of the sheep tested.
Anahtar Kelime: Awassi Inverdale PCR-RFLP BMP15 gene

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Abulyazid I, Sharada HM, Abdalla MS, Saleh HM, Hassanin WF. 2011. FecX1 gene as a monitor for the production of twins in the Egyptian sheep. Roavs, 1 (4): 217-219.
  • Aksoy Y, Ugurlu M, Onenc A, Sirin E, Sen U, Ciçek U, Ulutas Z, Kuran M. 2019. Meat production characteristics of Turkish native breeds: II. meat quality, fatty acid, and cholesterol profile of lambs. Arch Anim Breed, 62: 41–48.
  • Davis GH, Balakrishnan L, Ross IK, Wilson T, Galloway SM, Lumsden BM, Hanrahan JP, Mullen M, Mao XZ, Wang GL. 2006. Investigation of the Booroola (FecB) and Inverdale (FecXI) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries. Anim Reprod Sci, 92 (1-2): 87-96.
  • Davis GH, Galloway SM, Ross IK, Gregan SM, Ward J, Nimbkar BV, Ghalsasi PM, Nimbkar C, Gray GD, Inounu I. 2002. DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation. Biol Reprod, 66 (6): 1869-1874.
  • Davis GH, McEwan JC, Fennessy PF, Dodds KG, Farquhar PA. 1991. Evidence for the presence of a major gene influencing ovulation rate on the X chromosome of sheep. Biol Reprod, 44 (4): 620–624.
  • Davis GH, McEwan JC, Fennessy PF, Dodds KG, McNatty KP, Wai-Sum O. 1992. Infertility due to bilateral ovarian hypoplasia in sheep homozygous (FecX1 FecX1) for the Inverdale prolificacy gene located on the X chromosome. Biol Reprod, 46 (4): 636-640.
  • Davis GH. 2005. Major genes affecting ovulation rate in sheep. Genet Sel Evol, 37: 11-23.
  • Dinçel D, Ardıçlı S, Soyudal B, Er M, Alpay F, Şamlı H, Balcı F. 2015. Analysis of FecB, BMP15 and CAST gene mutations in Sakiz sheep. Kafkas Univ Vet Fak Derg, 21 (4): 483-488.
  • Drouilhet L, Mansanet C, Sarry J, Tabet K, Bardou P. 2013. The Highly prolific phenotype of Lacaune Sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary. PLoS Genet, 9 (9): 1-12.
  • Galal S, Gürsoy O, Shaat I. 2008. Awassi sheep as a genetic resource and efforts for their genetic improvement—A review. Small Rumin Res, 79: 99-108.
  • Galloway SM, McNatty KP, Cambridge LM, Laitinen MP, Juengel JL, Jokiranta TS, McLaren RJ, Luiro K, Dodds KG, Montgomery GW. 2000. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet, 25 (3): 279-283.
  • Gürsel E, Akış I, Durak H, Mengi A, Öztabak K. 2011. Determination of BMP-15, BMPR-1B and GDF-9 gene mutations of the indigenous sheep breeds in Turkey. Kafkas Univ Vet Fak Derg, 17 (5): 725-729.
  • Jansson T. 2014. Genes involved in ovulation rate and litter size in sheep. B.S thesis, Swedish University of Agricultural Sciences Faculty of Veterinary Medicine and Animal Science, Uppsala, pp 19.
  • Karslı T, Şahin E, Karslı BA, Eren MG, Balcıoğlu MS. 2011. Kangal ve Güney Karaman koyunlarinda FecB FecXG, FecXH allellerinin PCR-RFLP yöntemi kullanılarak araştırılması. Lalahan Hay Araşt Enst Der, 51 (2): 71-80
  • Kırıkçı, K, Çam MA. 2020. Türkiye yöresel yeni koyun tipi Of koyunlarında GDF9 (FecG1) gen polimorfizmin PCR-RFLP yöntemi ile Araştırılması. MJAVL, 10 (2): 98-102.
  • Meydan H, Ozkan MM, Yildiz MA, Goldmann W. 2013. Novel polymorphisms in ovine prion protein gene. Anim Genet, 44(5):588-591.
  • Pramod RK, Sharma SK, Kumar R, Rajan A. 2013. Genetics of ovulation rate in farm animals.Vet.World, 6 (11): 833-838.
  • Roy J, Polley S, De S, Mukherjee A, Batabyal S, Pan S, Brahma B, Datta TK, Goswami SL. 2011. Polymorphism of fecundity genes (FecB, FecX, and FecG) in the Indian Bonpala sheep.Anim Biotechnol, 22 (3): 151–162.
  • Üstüner H, Oğan MM. 2013. Main productive performance of Awassi sheep in the Central Anatolian Region of Turkey. Turkish J Vet Anim Sci, 37 (3): 271-276.
  • Yetisgin OS, Sen U. 2020. Resilience to drought in semi-desert sheep: Effects of water restriction during pregnancy on placental efficiency in the Awassi breed. Anim Sci J, 91: e13494.
APA GEDIK Y (2021). Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. , 130 - 132. 10.47115/bsagriculture.988347
Chicago GEDIK YASEMIN Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. (2021): 130 - 132. 10.47115/bsagriculture.988347
MLA GEDIK YASEMIN Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. , 2021, ss.130 - 132. 10.47115/bsagriculture.988347
AMA GEDIK Y Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. . 2021; 130 - 132. 10.47115/bsagriculture.988347
Vancouver GEDIK Y Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. . 2021; 130 - 132. 10.47115/bsagriculture.988347
IEEE GEDIK Y "Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep." , ss.130 - 132, 2021. 10.47115/bsagriculture.988347
ISNAD GEDIK, YASEMIN. "Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep". (2021), 130-132. https://doi.org/10.47115/bsagriculture.988347
APA GEDIK Y (2021). Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. Black Sea Journal of Agriculture, 4(4), 130 - 132. 10.47115/bsagriculture.988347
Chicago GEDIK YASEMIN Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. Black Sea Journal of Agriculture 4, no.4 (2021): 130 - 132. 10.47115/bsagriculture.988347
MLA GEDIK YASEMIN Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. Black Sea Journal of Agriculture, vol.4, no.4, 2021, ss.130 - 132. 10.47115/bsagriculture.988347
AMA GEDIK Y Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. Black Sea Journal of Agriculture. 2021; 4(4): 130 - 132. 10.47115/bsagriculture.988347
Vancouver GEDIK Y Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep. Black Sea Journal of Agriculture. 2021; 4(4): 130 - 132. 10.47115/bsagriculture.988347
IEEE GEDIK Y "Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep." Black Sea Journal of Agriculture, 4, ss.130 - 132, 2021. 10.47115/bsagriculture.988347
ISNAD GEDIK, YASEMIN. "Screening for Inverdale (FecXI) Mutation in BMP15 Gene in Prolific Turkish Awassi Sheep". Black Sea Journal of Agriculture 4/4 (2021), 130-132. https://doi.org/10.47115/bsagriculture.988347