A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis
Yıl: 2022 Cilt: 11 Sayı: 2 Sayfa Aralığı: 102 - 106 Metin Dili: İngilizce DOI: 10.5505/respircase.2022.67984 İndeks Tarihi: 21-07-2022
A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis
Öz: HIV (Human Immunodeficiency Virus) is the virus that
causes AIDS (Acquired Immune Deficiency Syndrome),
while PCP (Pneumocystis jiroveci pneumonia), tuberculosis,
CMV (Cytomegalovirus) and candidiasis are
the OIs (opportunistic infections) occurring due to
immune deficiency. OIs, and bacterial pneumonias in
particular, are the most common causes of mortality,
which makes the screening and prophylactic therapy
for OIs necessary. The synergy between tuberculosis
and HIV has long been known, and worsens the
prognosis. PCP is an OI that is caused by a fungus
named P. jiroveci. COVID-19 has emerged as a new
cause of death among AIDS patients. Screening and
prophylactic therapy for Ols is vital for patients with
AIDS, however, mortality may be high due to delays
in screening and prophylaxis in those whose HIV
positivity is detected coincidentally. We report here on
a patient who applied to our hospital with suspected
COVID-19 pneumonia who was found during followup
to be HIV positive with PCP and pulmonary tuberculosis.
Anahtar Kelime: AIDS, PCP ve Tüberküloz Tanıları Alan COVİD-19 Şüpheli bir Olgu
Öz: HIV (İnsan İmmün Yetmezlik Virüsü) immün sistemi
zayıflatan, AIDS (Kazanılmış Bağışıklık Yetersizliği
Sendromu) hastalığına yol açan viral bir enfeksiyondur.
İmmün sistemin zayıflaması ile birlikte, tüberküloz,
PCP (Pneumocystis jiroveci pnömonisi), CMV
(sitomegalovirüs), kandida gibi fırsatçı enfeksiyonlara
olanak sağlamaktadır. En yüksek mortaliteyi oluşturan
durumlar fırsatçı enfeksiyonlardır. Bu durum AIDS
hastalarında fırsatçı enfeksiyonlara yönelik tarama ve
profilaksi uygulanmasını gerekli kılmıştır. Tüberküloz
ile HIV birlikteliği uzun zamandır bilinmekte ve prognozu
kötüleştirmektedirler. PCP ise günümüzde mantar
olarak kabul edilen P. jirovecii etkenli fırsatçı bir
pnömonidir. Covid -19 pandemisi ile birlikte de AIDS
hastalarında yeni bir mortalite sebebi ortaya çıkmıştır.
AIDS hastalarının bu fırsatçı enfeksiyonlara karşı
taranması, profilaktik tedavi alması ve erkenden
tedavi almaları hayati önem taşımaktadır. Ancak HIV
pozitifliği rastlantısal olarak saptanan kişilerde tarama
ve profilaksi gecikmesinden ötürü mortalite yüksek
seyredebilmektedir. Bu yazıda Covid-19 pnömonisi
şüphesi ile hastanemize başvuran bir hastanın HIV
pozitif tespit edilip PCP ve takibinde akciğer tüberkülozu
saptanması anlatılmaktadır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
- 1. WHO 2020, https://www.who.int/health-topics/hiv-aids.
- 2. Aunsborg J W, Hønge B L, Jespersen S, Rudolf F, Medina C, Correira FG, et al. A clinical score has utility in tuberculosis case-finding among patients with HIV: A feasibility study from Bissau. Int J Infect Dis 2020; 92: 78-84. [CrossRef]
- 3. Chung-Delgado K, Guillen-Bravo S, Revilla-Montag A, Bernabe-Ortiz A. Mortality among MDR-TB cases: comparison with drug-susceptible tuberculosis and associated factors. PloS One 2015; 10:e0119332. [CrossRef]
- 4. Chepkondol GK, Jolly PE, Yatich N, Mbowe O, Jaoko WG. Types and prevalence of HIV-related opportunistic infections/conditions among HIV-positive patients attending Kenyatta National Hospital in Nairobi, Kenya. Afr Health Sci 2020; 20:615-24. [CrossRef]
- 5. Rozaliyani A, Wiyono WH, Nawas MA, Sijam R, Adawiyah R, Tugiran M, et al. Laboratory findings and clinical characteristics of Pneumocystis pneumonia and tuberculosis infection among HIV-infected patients with pulmonary infiltrates in Jakarta, Indonesia. Trop Biomed 2020; 37:1117-23. [CrossRef]
- 6. Çeviker SA, Günal Ö. Bilateral pnömoni kliniği ile tesadüfen tanı konulan AIDS olgusu. Flora Dergisi 2019; 24:67-72. [CrossRef]
- 7. Blanco JL, Ambrosioni J, Garcia F, Martínez E, Soriano A, Mallolas J, et al. COVID-19 in patients with HIV: clinical case series. The Lancet HIV 2020; 7:e314-6. [CrossRef]
- 8. Ceylan N, Savaş R. Radiological findings of COVID-19 pneumonia. Eurasian J Pulmonol 2020; 22:19-24. [CrossRef]
- 9. Türkiye Cumhuriyeti Sağlık Bakanlığı. Tüberküloz tanı ve tedavi kılavuzu. (Republic of Turkey, Ministry of Health. Tuberculosis Diagnosis and Treatment Guidelines). Ankara 2019.
- 10. DeRiemer K, Kawamura LM, Hopewell PC, Daley CL. Quantitative impact of human immunodeficiency virus infection on tuberculosis dynamics. Am J Respir Crit Care Med 2007; 176:936-44. [CrossRef]
- 11. Abdool Karim S S, Naidoo K, Grobler A, et al. Integration of antiretroviral therapy with tuberculosis treatment. N Engl J Med 2011; 365: 1492-501. [CrossRef]
- 12. Castro JG, Manzi G, Espinoza L, Campos M, Boulanger C. Concurrent PCP and TB pneumonia in HIV infected patients. Scand J Infect Dis 2007; 39:1054-8. [CrossRef]
- 13. Tchatchouang S, Nzouankeu A, Donkeng V, Eyangoh S, Ngando L, Penlap V, et al. Prevalence of opportunistic pathogens Pneumocystis jiroveci and tubercle bacilli in HIV-infected patients with respiratory infections in Yaounde, Cameroon. AIDS Res Hum Retroviruses 2019; 35:428-9. [CrossRef]
APA | saymaz z, Özkara Ş (2022). A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. , 102 - 106. 10.5505/respircase.2022.67984 |
Chicago | saymaz zeynep tilbe,Özkara Şeref A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. (2022): 102 - 106. 10.5505/respircase.2022.67984 |
MLA | saymaz zeynep tilbe,Özkara Şeref A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. , 2022, ss.102 - 106. 10.5505/respircase.2022.67984 |
AMA | saymaz z,Özkara Ş A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. . 2022; 102 - 106. 10.5505/respircase.2022.67984 |
Vancouver | saymaz z,Özkara Ş A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. . 2022; 102 - 106. 10.5505/respircase.2022.67984 |
IEEE | saymaz z,Özkara Ş "A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis." , ss.102 - 106, 2022. 10.5505/respircase.2022.67984 |
ISNAD | saymaz, zeynep tilbe - Özkara, Şeref. "A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis". (2022), 102-106. https://doi.org/10.5505/respircase.2022.67984 |
APA | saymaz z, Özkara Ş (2022). A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. Respiratory Case Reports, 11(2), 102 - 106. 10.5505/respircase.2022.67984 |
Chicago | saymaz zeynep tilbe,Özkara Şeref A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. Respiratory Case Reports 11, no.2 (2022): 102 - 106. 10.5505/respircase.2022.67984 |
MLA | saymaz zeynep tilbe,Özkara Şeref A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. Respiratory Case Reports, vol.11, no.2, 2022, ss.102 - 106. 10.5505/respircase.2022.67984 |
AMA | saymaz z,Özkara Ş A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. Respiratory Case Reports. 2022; 11(2): 102 - 106. 10.5505/respircase.2022.67984 |
Vancouver | saymaz z,Özkara Ş A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis. Respiratory Case Reports. 2022; 11(2): 102 - 106. 10.5505/respircase.2022.67984 |
IEEE | saymaz z,Özkara Ş "A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis." Respiratory Case Reports, 11, ss.102 - 106, 2022. 10.5505/respircase.2022.67984 |
ISNAD | saymaz, zeynep tilbe - Özkara, Şeref. "A Case of Suspected COVID-19 Identified with AIDS, PCP and Tuberculosis". Respiratory Case Reports 11/2 (2022), 102-106. https://doi.org/10.5505/respircase.2022.67984 |