Viral etiology and symptoms of acute upper respiratory tract infections in children

OĞUZ, FATMA; TOPRAK, SADIK; SIDAL, Müjgan; ASLAN, Selvi Seyhan; Badur, selim; Cakal, Bulent; KILIÇ, Ayşe; ÜNÜVAR, Emin; Yıldız, İsmail

Viral etiology and symptoms of acute upper respiratory tract infections in children

Emin ÜNÜVAR, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Pediatri Anabilim Dalı, İstanbul, Türkiye)

İsmail YILDIZ, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Pediatri Anabilim Dalı, İstanbul, Türkiye)

Ayşe KILIÇ, (İstanbul Üniversitesi, Çocuk Sağlığı Enstitüsü, İstanbul, Türkiye)

Selvi Seyhan ASLAN, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Bülent ÇAKAL, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Sadık TOPRAK, (Gaziosmanpaşa Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Tokat, Türkiye)

Selim BADUR, (İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Fatma OĞUZ, (İstanbul Üniversitesi, Çocuk Sağlığı Enstitüsü, İstanbul, Türkiye)

Müjgan SIDAL (İstanbul Üniversitesi, Çocuk Sağlığı Enstitüsü, İstanbul, Türkiye)

Turkish Journal of Medical Sciences

6 1

Yıl: 2009 Cilt: 39 Sayı: 1 Sayfa Aralığı: 29 - 35 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Viral etiology and symptoms of acute upper respiratory tract infections in children

Öz:

Amaç: İstanbul’da yaşayan çocuklarda akut üst solunum yolu enfeksiyonlarının viral etiyolojisinin ve etkenlere spesifik klinik bulgularının saptanması. Yöntemler: Prospektif, klinik bu araştırma 1-180 ay yaş aralığında olan 234 üst solunum yolu enfeksiyonlu çocukla ayaktan yürütüldü. Vakaların klinik bulguları kaydedildikten sonra, nazal sürüntü örneği alındı. Bu örnekte influenza-A ve B, adenovirüs, respiratuar sinsisyel virüs, parainfluenza virüsler direk flöresan antikor, PCR ve hücre kültür yöntemleri kullanılarak 201 örnekte araştırıldı. Bulgular: Virüs izole edebilme oranımız % 29.8 idi (60/201). En sık izole edilenler sırasıyla influenza-A (% 36.6), adenovirüs (% 28.4), parainfluenza (% 14.9), respiratuar sinsisyal virüs (% 13.5) idi. İnfluenza-A vakalarının tümü H3N2 tipindeydi. İki yaş altında en sık respiratuar sinsisyal virüs (% 63) ile adenovirüs (% 59) iken, iki yaş üzerinde influenza-A baskındı (% 82). Klinik bulgular viral etkenlere göre spesifik bir farkılık göstermiyordu. Sonuç: Çocuklarda üst solunum yolu enfeksiyonlarında viral etiyoloji % 29.8 oranında gösterilebildi ve en sık etkenler influenza-A, adenovirüs ve parainfluenza virüstü.

Anahtar Kelime: Kültür ortamı Polimeraz zincir reaksiyonu Etiyoloji Solunum yolu enfeksiyonları Çocuk Floresans antikor tekniği

Konular: Cerrahi

Çocuklarda akut üst solunum yolu enfeksiyonlarının viral etiyolojisi ve klinik özellikleri

Öz:

Aims: To determine viral causes of acute upper respiratory tract infections and clinical findings in children living in Istanbul, Turkey. Materials and Methods: This prospective study was carried out in 234 outpatient children (age range: 1- 180 months) with acute upper respiratory tract infections, seen in the outpatient clinic at Istanbul Medical School Children’s Hospital. After clinical findings were recorded, nasal swab specimens were taken. In 201 specimens collected, influenza-A and -B, adenovirus, respiratory syncytial virus, and parainfluenza viruses were studied using direct fluorescence antibody, polymerase chain reaction (PCR), and cell culture techniques. Results: Rate of virus isolation was 29.8% (60/201). The viruses isolated in decreasing order were influenza- A (36.6%), adenovirus (28.4%), parainfluenza (14.9%), and respiratory syncytial virus (13.5%). All influenza-A cases were type H3N2. The common viruses in children less than 2 years of age were respiratory syncytial virus (63%) and adenovirus (59%), whereas influenza-A was dominant over 2 years of age (82%). Clinical symptoms did not differ among the different viral causes. Conclusions: Viral etiologies in children with acute upper respiratory tract infections were shown at a rate of 29.8% and the most common causes were influenza-A, adenovirus and parainfluenza viruses.

Anahtar Kelime: Child Fluorescent Antibody Technique Culture Media Polymerase Chain Reaction Etiology Respiratory Tract Infections

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÜNÜVAR E, Yıldız İ, KILIÇ A, ASLAN S, Cakal B, TOPRAK S, Badur s, OĞUZ F, SIDAL M (2009). Viral etiology and symptoms of acute upper respiratory tract infections in children. , 29 - 35.
Chicago	ÜNÜVAR Emin,Yıldız İsmail,KILIÇ Ayşe,ASLAN Selvi Seyhan,Cakal Bulent,TOPRAK SADIK,Badur selim,OĞUZ FATMA,SIDAL Müjgan Viral etiology and symptoms of acute upper respiratory tract infections in children. (2009): 29 - 35.
MLA	ÜNÜVAR Emin,Yıldız İsmail,KILIÇ Ayşe,ASLAN Selvi Seyhan,Cakal Bulent,TOPRAK SADIK,Badur selim,OĞUZ FATMA,SIDAL Müjgan Viral etiology and symptoms of acute upper respiratory tract infections in children. , 2009, ss.29 - 35.
AMA	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M Viral etiology and symptoms of acute upper respiratory tract infections in children. . 2009; 29 - 35.
Vancouver	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M Viral etiology and symptoms of acute upper respiratory tract infections in children. . 2009; 29 - 35.
IEEE	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M "Viral etiology and symptoms of acute upper respiratory tract infections in children." , ss.29 - 35, 2009.
ISNAD	ÜNÜVAR, Emin vd. "Viral etiology and symptoms of acute upper respiratory tract infections in children". (2009), 29-35.

APA	ÜNÜVAR E, Yıldız İ, KILIÇ A, ASLAN S, Cakal B, TOPRAK S, Badur s, OĞUZ F, SIDAL M (2009). Viral etiology and symptoms of acute upper respiratory tract infections in children. Turkish Journal of Medical Sciences, 39(1), 29 - 35.
Chicago	ÜNÜVAR Emin,Yıldız İsmail,KILIÇ Ayşe,ASLAN Selvi Seyhan,Cakal Bulent,TOPRAK SADIK,Badur selim,OĞUZ FATMA,SIDAL Müjgan Viral etiology and symptoms of acute upper respiratory tract infections in children. Turkish Journal of Medical Sciences 39, no.1 (2009): 29 - 35.
MLA	ÜNÜVAR Emin,Yıldız İsmail,KILIÇ Ayşe,ASLAN Selvi Seyhan,Cakal Bulent,TOPRAK SADIK,Badur selim,OĞUZ FATMA,SIDAL Müjgan Viral etiology and symptoms of acute upper respiratory tract infections in children. Turkish Journal of Medical Sciences, vol.39, no.1, 2009, ss.29 - 35.
AMA	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M Viral etiology and symptoms of acute upper respiratory tract infections in children. Turkish Journal of Medical Sciences. 2009; 39(1): 29 - 35.
Vancouver	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M Viral etiology and symptoms of acute upper respiratory tract infections in children. Turkish Journal of Medical Sciences. 2009; 39(1): 29 - 35.
IEEE	ÜNÜVAR E,Yıldız İ,KILIÇ A,ASLAN S,Cakal B,TOPRAK S,Badur s,OĞUZ F,SIDAL M "Viral etiology and symptoms of acute upper respiratory tract infections in children." Turkish Journal of Medical Sciences, 39, ss.29 - 35, 2009.
ISNAD	ÜNÜVAR, Emin vd. "Viral etiology and symptoms of acute upper respiratory tract infections in children". Turkish Journal of Medical Sciences 39/1 (2009), 29-35.