Pozitron emisyon tomografi ve radyoterapi tedavi planlama

DEMİR, MUSTAFA; OKUTAN, MURAT; DEMİR, Bayram

Pozitron emisyon tomografi ve radyoterapi tedavi planlama

Bayram DEMİR, (İstanbul Üniversitesi, Fen Fakültesi, Fizik Bölümü, İstanbul, Türkiye)

Murat OKUTAN, (İstanbul Üniversitesi, Onkoloji Enstitüsü, İstanbul, Türkiye)

Mustafa DEMİR (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İstanbul, Türkiye)

Türk Onkoloji Dergisi

2 1

Yıl: 2009 Cilt: 24 Sayı: 2 Sayfa Aralığı: 88 - 97 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Pozitron emisyon tomografi ve radyoterapi tedavi planlama

Öz:

Pozitron emisyon tomografi (PET), insan vücudundaki organlar ve metabolizmaların görüntülenmesini sağlayan bir radyoizotop görüntüleme tekniğidir. Görüntüleme ilkesi olarak pozitronun-elektron yok olma olayı sonucunda ortaya çıkan iki adet 511 KeV enerjili yok olma fotonun eş zamanlı deteksiyonu kullanılmaktadır. Uygulamada C-11, N-13, O-15, F-18 gibi pozitron yayınlayan radyoizotopların glikoz molekülü ile birleştirilmesi sonucu elde edilen radyofarmasötik (örneğin; F-18-FDG) hastaya kan yolu ile verilir. Vücuttaki anormal yapılarda biriken bu radyofarmasötikten elde edilen 511 KeV fotonları PET cihazında algılanarak bilgisayarda vücudun 3-boyutlu görüntüsü elde edilmektedir. Bu yazıda, PET'in temel çalışma ilkesi, PET sintilasyon kristalleri, PET radyoizotopları ve radyoterapi tedavi planlamada PET hakkında bilgiler verilecektir.

Anahtar Kelime:

Konular: Onkoloji

Positron emission tomography and radiotherapy treatment planning

Öz:

Positron emission tomography (PET) is a radioisotope imaging method for obtaining information on the status of organs and metabolisms within the human body. The imaging principle used in PET is the coincidence detection of two 511 KeV annihilation photons-originated electron-positron annihilation. In practice, a radiopharmaceutical (e.g., F-18-FDG) obtained by uniting a positron emitter radioisotope (e.g., C-11, N-13, O-15, F-18) and glucose molecule is given to the patient by way of blood injection. PET detects these 511 KeV annihilation photons accumulated in the abnormal structures and then three-dimensional imaging of the body is created by the computer. In this review of the imaging principle of PET, scintillation crystals, PET radioisotopes and PET for radiotherapy treatment planning are discussed.

Anahtar Kelime:

Konular: Onkoloji

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	DEMİR B, OKUTAN M, DEMİR M (2009). Pozitron emisyon tomografi ve radyoterapi tedavi planlama. , 88 - 97.
Chicago	DEMİR Bayram,OKUTAN MURAT,DEMİR MUSTAFA Pozitron emisyon tomografi ve radyoterapi tedavi planlama. (2009): 88 - 97.
MLA	DEMİR Bayram,OKUTAN MURAT,DEMİR MUSTAFA Pozitron emisyon tomografi ve radyoterapi tedavi planlama. , 2009, ss.88 - 97.
AMA	DEMİR B,OKUTAN M,DEMİR M Pozitron emisyon tomografi ve radyoterapi tedavi planlama. . 2009; 88 - 97.
Vancouver	DEMİR B,OKUTAN M,DEMİR M Pozitron emisyon tomografi ve radyoterapi tedavi planlama. . 2009; 88 - 97.
IEEE	DEMİR B,OKUTAN M,DEMİR M "Pozitron emisyon tomografi ve radyoterapi tedavi planlama." , ss.88 - 97, 2009.
ISNAD	DEMİR, Bayram vd. "Pozitron emisyon tomografi ve radyoterapi tedavi planlama". (2009), 88-97.

APA	DEMİR B, OKUTAN M, DEMİR M (2009). Pozitron emisyon tomografi ve radyoterapi tedavi planlama. Türk Onkoloji Dergisi, 24(2), 88 - 97.
Chicago	DEMİR Bayram,OKUTAN MURAT,DEMİR MUSTAFA Pozitron emisyon tomografi ve radyoterapi tedavi planlama. Türk Onkoloji Dergisi 24, no.2 (2009): 88 - 97.
MLA	DEMİR Bayram,OKUTAN MURAT,DEMİR MUSTAFA Pozitron emisyon tomografi ve radyoterapi tedavi planlama. Türk Onkoloji Dergisi, vol.24, no.2, 2009, ss.88 - 97.
AMA	DEMİR B,OKUTAN M,DEMİR M Pozitron emisyon tomografi ve radyoterapi tedavi planlama. Türk Onkoloji Dergisi. 2009; 24(2): 88 - 97.
Vancouver	DEMİR B,OKUTAN M,DEMİR M Pozitron emisyon tomografi ve radyoterapi tedavi planlama. Türk Onkoloji Dergisi. 2009; 24(2): 88 - 97.
IEEE	DEMİR B,OKUTAN M,DEMİR M "Pozitron emisyon tomografi ve radyoterapi tedavi planlama." Türk Onkoloji Dergisi, 24, ss.88 - 97, 2009.
ISNAD	DEMİR, Bayram vd. "Pozitron emisyon tomografi ve radyoterapi tedavi planlama". Türk Onkoloji Dergisi 24/2 (2009), 88-97.