Distribution of Colon Lesions in the Elderly

Objective: Screening and surveillance for colon lesions is very important, particularly given the increased incidence of benign and malign colon diseases with age. The aim of this study was to determine the frequency and characteristics of colon lesions in an elderly population in Turkey. Materials and Methods: This retrospective study was conducted in the gastroenterology clinic of the Erciyes University Faculty of Medicine Hospital. The histopathological results and demographic characteristics of 1004 elderly patients who underwent a colonoscopy with a biopsy between 2015 and 2019 were retrospectively analyzed. Results: A total of 1004 elderly patients were included in the study. The findings revealed that 592 (58.9%) of the patients had polyps, 121 (12.05%) had colitis, 23 (2.3%) had ileitis, 88 (8.7%) had colon carcinoma, 2 (0.2%) had amyloidosis, 34 (3.4%) had other histopathological diagnoses (in order of frequency, melanosis coli, lipoma, solitary rectal ulcer, neuroendocrine tumor, leiomyoma, mantle cell lymphoma, marginal zone lymphoma and 1ow grade dysplasia), and 22 patients had multiple synchronous pathologies. Conclusion: Colon pathology types and frequencies differ with advanced age. Appropriate colonoscopy screening programs and multiple histopathological sampling methods from each colon segment during colonoscopy offer early recognition of both benign and malignant colon lesions.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Lee SB, Oh JH, Park JH, Choi SP, Wee JH. Differences in youngest- old, middle-old, and oldest-old patients who visit the emergency department. Clin Exp Emerg Med 2018; 5(4): 249–55.
2. Büyükşimşek M, Kara İO. Aging biology, geriatric patient definition and oncological approaches to these patients. In: Ozcelik C, editor. Chest Surgery in the Elderly. 1st edition. Ankara: Turkish Clinics; 2019. p.1–5.
3. An R, Wilms E, Masclee AAM, Smidt H, Zoetendal EG, Jonkers D. Age-dependent changes in GI physiology and microbiota: time to reconsider? Gut 2018; 67(12): 2213–22.
4. Santoro A, Ostan R, Candela M, Biagi E, Brigidi P, Capri M, et al. Gut microbiota changes in the extreme decades of human life: a focus on centenarians. Cell Mol Life Sci 2018; 75(1): 129–48.
5. Dumic I, Nordin T, Jecmenica M, Stojkovic Lalosevic M, Milosavljevic T, et al. Gastrointestinal tract disorders in older age. Can J Gastroenterol Hepatol 2019; 2019: 6757524.
6. Smith BD, Smith GL, Hurria A, Hortobagyi GN, Buchholz TA. Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol 2009; 27(17): 2758–65.
7. Rex DK. Colorectal cancer screening. Gastrointest Endosc Clin N Am 2020; 30(3): XV–I.
8. Şahintürk Y, Çekin AH. Colon polyps localization, histology, and size - five years colonoscopic research. Endoskopi Gastrointestinal 2018; 26: 57–60.
9. Uçmak F, Tuncer ET, Ekin N, Büyükbayram H, Kaya M. Incidence and characteristics of colon polyps in Southeast Anatolian Region: A 5-Year evaluation. Turk J Colorectal Dis 2016; 2: 21–6.
10. Yanık S, Akkoca AN, Özdemir ZT, Sözütek D, Yılmaz EE, Sayar S. Evaluation of results of lower gastrointestinal endoscopic biopsi. Int J Clin Exp Med 2014; 7(12): 5820–5.
11. Oluyemi A, Awolola N, Oyedeji O. Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria. Pan African Med J 2016; 24: 333.
12. Mohammad S, Rind GH, Shah IA, Baloch I, Shah AA, Lakho S, et al. Colonoscopy findings: A single institution study from Pakistan. Cureus 2019; 11(11): e6167.
13. Bafandeh Y, Yazdanpanah F. Distribution pattern of colorectal diseases based on 2300 total colonoscopies. Gastroenterol Hepatol Bed Bench 2017; 10(2): 90–6.
14. Rex DK, Sullivan AW, Perkins AJ, Vemulapalli KC. Colorectal polyp prevalence and aspirational detection targets determined using high definition colonoscopy and a high level detector in 2017. Dig Liver Dis 2020; 52(1): 72–8.
15. Zhou H, Shen Z, Zhao J, Zhou Z, Xu Y. Distribution characteristics and risk factors of colorectal adenomas. [Article in Chinese]. Chinese J Gastrol Surg 2018; 21(6): 678–84.
16. UICC. Global cancer Data: GLOBOCAN, 2018. Available from: URL: www.uiccorg/new-global-cancer-data-globocan-2018. Accessed March 24, 2022.
17. Kara Y, Sarıcı İŞ, Kalaycı MU. Evaluation of the effectiveness of colon cancer screening program conducted in our region. İKSSTD 2019; 11(1): 31–6.
18. Ünal NG, Coşgun G, Korkut M, Özütemiz AÖ, Doğanavşargil B, Çakar B, et al. Epidemiologic and survival characteristics of patients with colorectal cancer in Ege University Medical Faculty database. Ege J Med 2019; 58(Supp): 68–77.
19. Ng SC, Shi HY, Hamidi N, Underwood FE, Tang W, Benchimol EI, et al. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. Lancet 2017; 390(10114): 2769–78. Erratum in: Lancet 2020; 396(10256): e56.
20. GBD 2017 Inflammatory Bowel Disease Collaborators. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol 2020; 5(1): 17–30.
21. Buran T. Inflammatory bowel disease; epidemiology, prevalence, incidence. Turkish Clinics J Gastroenterohepatol 2017; 10(1): 15–7.
22. Tozun N, Atug O, Imeryuz N, Hamzaoglu HO, Tiftikci A, Parlak E, et al; Members of the Turkish IBD Study Group. Clinical characteristics of inflammatory bowel disease in Turkey: a multicenter epidemiologic survey. J Clin Gastroenterol 2009; 43(1): 51–7.
23. Can G, Poşul E, Yılmaz B, Can H, Korkmaz U, Ermiş F, et al. Epidemiologic features of inflammatory bowel disease in Western Blacksea region of Turkey for the last 10 years: retrospective cohort study. Korean J Intern Med 2019; 34(3): 519–29.
24. Desport E, Bridoux F, Sirac C, Delbes S, Bender S, Fernandez B, et al; Centre national de référence pour l’amylose AL et les autres maladies par dépôts d’immunoglobulines monoclonales. Al amyloidosis. Orphanet J Rare Dis 2012; 7: 54.
25. Gertz MA, Dispenzieri A. Systemic amyloidosis recognition, prognosis, and therapy: A systematic review. JAMA 2020; 324(1): 79– 89.
26. Hemminki K, Li X, Försti A, Sundquist J, Sundquist K. Incidence and survival in non-hereditary amyloidosis in Sweden. BMC Public Health 2012; 12: 974.
27. Kyle RA, Larson DR, Kurtin PJ, Kumar S, Cerhan JR, Therneau TM, et al. Incidence of al amyloidosis in Olmsted County, Minnesota, 1990 through 2015. Mayo Clin Proc 2019; 94(3): 465–71.
28. Lim AY, Lee JH, Jung KS, Gwag HB, Kim DH, Kim SJ, et al. Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience. Korean J Intern Med 2015; 30(4): 496–505.

APA	Bulur O, Gürsoy S, Deniz K, Özbakır Ö, Güven K, yurci a, Can Sezgin G, Özel M, Bozkurt Burgucu B, Özden Y, Abdurahmanov V, YILDIRIM M (2022). Distribution of Colon Lesions in the Elderly. , 318 - 323. 10.14744/etd.2021.45087
Chicago	Bulur Oktay,Gürsoy Sebnem,Deniz Kemal,Özbakır Ömer,Güven Kadri,yurci alper,Can Sezgin Gülten,Özel Mustafa,Bozkurt Burgucu Burcu,Özden Yavuz,Abdurahmanov Vusal,YILDIRIM MİHRİBAN Distribution of Colon Lesions in the Elderly. (2022): 318 - 323. 10.14744/etd.2021.45087
MLA	Bulur Oktay,Gürsoy Sebnem,Deniz Kemal,Özbakır Ömer,Güven Kadri,yurci alper,Can Sezgin Gülten,Özel Mustafa,Bozkurt Burgucu Burcu,Özden Yavuz,Abdurahmanov Vusal,YILDIRIM MİHRİBAN Distribution of Colon Lesions in the Elderly. , 2022, ss.318 - 323. 10.14744/etd.2021.45087
AMA	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M Distribution of Colon Lesions in the Elderly. . 2022; 318 - 323. 10.14744/etd.2021.45087
Vancouver	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M Distribution of Colon Lesions in the Elderly. . 2022; 318 - 323. 10.14744/etd.2021.45087
IEEE	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M "Distribution of Colon Lesions in the Elderly." , ss.318 - 323, 2022. 10.14744/etd.2021.45087
ISNAD	Bulur, Oktay vd. "Distribution of Colon Lesions in the Elderly". (2022), 318-323. https://doi.org/10.14744/etd.2021.45087

APA	Bulur O, Gürsoy S, Deniz K, Özbakır Ö, Güven K, yurci a, Can Sezgin G, Özel M, Bozkurt Burgucu B, Özden Y, Abdurahmanov V, YILDIRIM M (2022). Distribution of Colon Lesions in the Elderly. Erciyes Medical Journal, 44(3), 318 - 323. 10.14744/etd.2021.45087
Chicago	Bulur Oktay,Gürsoy Sebnem,Deniz Kemal,Özbakır Ömer,Güven Kadri,yurci alper,Can Sezgin Gülten,Özel Mustafa,Bozkurt Burgucu Burcu,Özden Yavuz,Abdurahmanov Vusal,YILDIRIM MİHRİBAN Distribution of Colon Lesions in the Elderly. Erciyes Medical Journal 44, no.3 (2022): 318 - 323. 10.14744/etd.2021.45087
MLA	Bulur Oktay,Gürsoy Sebnem,Deniz Kemal,Özbakır Ömer,Güven Kadri,yurci alper,Can Sezgin Gülten,Özel Mustafa,Bozkurt Burgucu Burcu,Özden Yavuz,Abdurahmanov Vusal,YILDIRIM MİHRİBAN Distribution of Colon Lesions in the Elderly. Erciyes Medical Journal, vol.44, no.3, 2022, ss.318 - 323. 10.14744/etd.2021.45087
AMA	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M Distribution of Colon Lesions in the Elderly. Erciyes Medical Journal. 2022; 44(3): 318 - 323. 10.14744/etd.2021.45087
Vancouver	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M Distribution of Colon Lesions in the Elderly. Erciyes Medical Journal. 2022; 44(3): 318 - 323. 10.14744/etd.2021.45087
IEEE	Bulur O,Gürsoy S,Deniz K,Özbakır Ö,Güven K,yurci a,Can Sezgin G,Özel M,Bozkurt Burgucu B,Özden Y,Abdurahmanov V,YILDIRIM M "Distribution of Colon Lesions in the Elderly." Erciyes Medical Journal, 44, ss.318 - 323, 2022. 10.14744/etd.2021.45087
ISNAD	Bulur, Oktay vd. "Distribution of Colon Lesions in the Elderly". Erciyes Medical Journal 44/3 (2022), 318-323. https://doi.org/10.14744/etd.2021.45087