The fact that employees work in an environment where their physical and mental health is protected serves both individual and society benefits. The level of risk in terms of occupational health and safety differs according to the sector in which it operates. Determining the risk levels of the sectors will help to minimize the negative situations that may arise. For this purpose, 7 criteria representing occupational accidents and diseases were determined in the research, and 88 sectors in the economic activity classification were considered as an alternative set. The analyzes were applied with the statistics of the year 2020 published by the Social Security Institution. With the grey relational analysis method, a ranking was obtained by assuming that the criteria were of equal importance. Then, a new ranking was made by using the CRITIC method, in which the criterion weights were determined objectively, and the grey relational analysis method together. In both cases, it has been determined that the riskiest sector in terms of occupational health and safety is building construction, while the second and third rank is the manufacture of fabricated metal products and human health services. The sectors with the lowest risk level were determined as the undifferentiated goods and services produced by international organizations and agency activities and households for their own use