Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis

DUMAN, FURKAN; Can, Handan; Leventoglu, Alev

doi:10.4274/tnd.2022.24992

Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis

Furkan DUMAN, (Ufuk University Faculty of Arts and Sciences, Department of Psychology, Ankara, Turkey)

Handan CAN, (Bursa Uludag University Faculty of Arts and Sciences, Department of Psychology, Bursa, Turkey)

Alev LEVENTOĞLU (Ufuk University Faculty of Medicine, Department of Neurology, Ankara, Turkey)

Türk Nöroloji Dergisi

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Yıl: 2022 Cilt: 28 Sayı: 3 Sayfa Aralığı: 162 - 168 Metin Dili: İngilizce DOI: 10.4274/tnd.2022.24992 İndeks Tarihi: 21-05-2023

Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis

Öz:

Objective: To compare patients with relapsing-remitting multiple sclerosis (RRMS) and healthy individuals in terms of short-term memory (STM), working memory (WM) and executive functions. Materials and Methods: The sample consisted of 33 patients with RRMS and 26 healthy participants. The groups were matched in terms of age, gender, level of education and hand dominance. The socio-demographic characteristics of the participants were recorded; and they were evaluated with Beck depression inventory and state/trait anxiety inventory. Visual aural digit span test B form, Wisconsin card sorting test, backward digit span task, stroop test T-BAG form, Wechsler memory scale: Revised form visual memory span subtest (WMS-R/VMS) and trail making test (TMT) for cognitive functions. Results: There was no statistically significant difference between groups in terms of depression and anxiety scores (p>0.05). Backward visual memory span calculated from WMS-R/VMS was significantly lower (p<0.05) in the RRMS group. However, there was no significant difference between groups in WMS-R/ VMS and TMT scores (p>0.05). Conclusion: Results of this study indicate that patients with RRMS have lower visuo-spatial sketchpad capacity in their WM. However, there was no significant difference between patients with RRMS and healthy controls in terms of verbal and visuo-spatial STM capacity, phonological loop capacity in WM, perseveration, conceptualization, inhibition and set shifting skills.

Anahtar Kelime:

Relapsing-remitting Multipl Sklerozlu Hastaların Kısa Süreli Bellek, Çalışma Belleği ve Yönetici İşlevlerinin Değerlendirilmesi

Öz:

Amaç: Relapsing-remitting multipl sklerozlu (RRMS) hastalar ile sağlıklı bireyleri kısa süreli bellek, çalışma belleği ve yönetici işlevler açısından karşılaştırmaktır. Gereç ve Yöntem: Araştırmaya RRMS tanısı alan 33 hasta (RRMS grubu) ile yaş, cinsiyet, eğitim düzeyi ve el tercihi bakımından eşleştirilen 26 sağlıklı katılımcı (kontrol grubu) dahil edilmiştir. Katılımcıların sosyo-demografik özellikleri kaydedilmiştir ve katılımcılara Beck depresyon envanteri ile durumluk/ sürekli kaygı envanteri uygulanmıştır. Katılımcılar bilişsel işlevler görsel-işitsel sayı dizisi testi B formu (GİSD-B), Wisconsin kart eşleme testi (WKET), geriye doğru sayı dizisi görevi (GDSD), stroop testi T-BAG formu, Wechsler bellek ölçeği geliştirilmiş formunun (WBÖGF) alt testlerinden biri olan görsel bellek uzamı alt testi (GBU) ve iz sürme testi (İST) kullanılarak değerlendirilmiştir. Bulgular: Gruplar arasında depresyon ve kaygı puanları açısından istatistiksel olarak anlamlı bir fark bulunmamıştır (p>0,05). RRMS grubunun WBÖGF’nin GBU alt testinden hesaplanan ters görsel bellek uzamı daha düşüktür (p<0,05). Gruplar arasında GİSD-B, WKET, GDSD, WBÖGF’nin GBU alt testinden hesaplanan düz görsel bellek uzamı ve İST puanları açısından anlamlı bir fark bulunmamıştır (p>0,05). Sonuç: Mevcut araştırmada RRMS’li hastaların çalışma belleğindeki görsel-mekansal kopyalama (sözel olmayan bilgi) kapasitesinin düşük olduğu saptanmıştır. Sözel olan ve olmayan kısa süreli bellek kapasitesi, çalışma belleğindeki fonolojik döngü (sözel bilgi) kapasitesi ile yönetici işlevlerden perseverasyon yapma eğilimi, kavramsallaştırma/irdeleme, inhibisyon (bozucu etkiye karşı koyma) ve set değiştirme becerileri açısından RRMS grubu ile kontrol grubu arasında istatistiksel olarak anlamlı bir farklılık olmadığı saptanmıştır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	DUMAN F, Can H, Leventoglu A (2022). Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. , 162 - 168. 10.4274/tnd.2022.24992
Chicago	DUMAN FURKAN,Can Handan,Leventoglu Alev Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. (2022): 162 - 168. 10.4274/tnd.2022.24992
MLA	DUMAN FURKAN,Can Handan,Leventoglu Alev Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. , 2022, ss.162 - 168. 10.4274/tnd.2022.24992
AMA	DUMAN F,Can H,Leventoglu A Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. . 2022; 162 - 168. 10.4274/tnd.2022.24992
Vancouver	DUMAN F,Can H,Leventoglu A Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. . 2022; 162 - 168. 10.4274/tnd.2022.24992
IEEE	DUMAN F,Can H,Leventoglu A "Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis." , ss.162 - 168, 2022. 10.4274/tnd.2022.24992
ISNAD	DUMAN, FURKAN vd. "Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis". (2022), 162-168. https://doi.org/10.4274/tnd.2022.24992

APA	DUMAN F, Can H, Leventoglu A (2022). Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. Türk Nöroloji Dergisi, 28(3), 162 - 168. 10.4274/tnd.2022.24992
Chicago	DUMAN FURKAN,Can Handan,Leventoglu Alev Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. Türk Nöroloji Dergisi 28, no.3 (2022): 162 - 168. 10.4274/tnd.2022.24992
MLA	DUMAN FURKAN,Can Handan,Leventoglu Alev Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. Türk Nöroloji Dergisi, vol.28, no.3, 2022, ss.162 - 168. 10.4274/tnd.2022.24992
AMA	DUMAN F,Can H,Leventoglu A Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. Türk Nöroloji Dergisi. 2022; 28(3): 162 - 168. 10.4274/tnd.2022.24992
Vancouver	DUMAN F,Can H,Leventoglu A Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis. Türk Nöroloji Dergisi. 2022; 28(3): 162 - 168. 10.4274/tnd.2022.24992
IEEE	DUMAN F,Can H,Leventoglu A "Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis." Türk Nöroloji Dergisi, 28, ss.162 - 168, 2022. 10.4274/tnd.2022.24992
ISNAD	DUMAN, FURKAN vd. "Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis". Türk Nöroloji Dergisi 28/3 (2022), 162-168. https://doi.org/10.4274/tnd.2022.24992