Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey
Yıl: 2023 Cilt: 28 Sayı: 3 Sayfa Aralığı: 341 - 352 Metin Dili: İngilizce DOI: 10.5578/flora.20239704 İndeks Tarihi: 28-10-2023
Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey
Öz: Introduction: Antimicrobial resistance is common due to inappropriate and overuse of antimicrobial agents. This study aimed to evaluate the knowledge, attitudes, and practices of the public about antibiotic use and resistance in Türkiye. Materials and Methods: In this study, a cross-sectional study design was used for a population-based survey. An online survey was conducted from June to September 2021. Results: 937 people (87.5%) responded to the questionnaire. About half of the respondents answered correctly that amoxicillin was an antibiotic and ibuprofen was not an antibiotic. 31.8% of the respondents considered that antibiotics were effective against viruses. Most of the respondents (88.2%) disagreed with the idea that they would not be happy if the physician did not prescribe antibiotics. 63.7% of the respondents declared that they never stopped using antibiotics when they believed they were cured. Conclusion: The study shows that the participants have a good attitude towards antibiotic use and resistance despite the lack of knowledge and practices.
Anahtar Kelime: Türkiye’de Antibiyotik Kullanımı ve Direncine İlişkin Halkın Bilgi, Tutum ve Uygulamaları: Kesitsel Bir Araştırma
Öz: Giriş: Antimikrobiyal ajanların uygunsuz ve aşırı kullanımı nedeniyle antimikrobiyal direnç giderek yaygınlaşmaktadır. Çalışmamızın amacı, Türkiye’de halkın antibiyotik kullanımı ve direnci ile ilgili bilgi, tutum ve uygulamalarını değerlendirmektir. Materyal ve Metod: Bu çalışmada, popülasyon temelli anket için kesitsel çalışma tasarımı kullanılmıştır. Haziran-Eylül 2021 arasında çevrim içi bir anket yapılmıştır. Bulgular: Ankete 937 kişi (%87.5) yanıt vermiştir. Ankete katılanların yaklaşık yarısı, amoksisilinin bir antibiyotik olduğunu ve ibupro- fenin bir antibiyotik olmadığını doğru yanıtlamıştır. Ankete katılanların %31.8’i antibiyotiklerin virüslere karşı etkili olduğunu düşün- müştür. Ankete katılanların çoğu (%88.2) hekimin antibiyotik yazmaması durumunda mutlu olmayacakları fikrine katılmamıştır. Ankete katılanların %63.7’si ise iyileştiğine inandıklarında antibiyotik kullanmayı asla bırakmadıklarını belirtmiştir. Sonuç: Araştırmamız, katılımcıların bilgi ve uygulama eksikliğine rağmen antibiyotik kullanımına ve direncine karşı iyi bir tutum içinde olduklarını göstermektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Laws M, Shaaban A, Rahman KM. Antibiotic resistance breakers: Current approaches and future directions. FEMS Microbiol Rev 2019;43:490-516. https://doi.org/10.1093/ femsre/fuz014
- 2. Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: A global multifaceted phenomenon. Pathog Glob Health 2015;109:309-18. https://doi.org/10.1179/2047773215Y.0000000030
- 3. Shibl A, Memish Z, Osoba A. Antibiotic resistance in developing countries. J Chemother 2001;13:40-4. https://doi. org/10.1080/1120009X.2001.11782327
- 4. Versporten A, Bolokhovets G, Ghazaryan L, Abilova V, Pyshnik G, Spasojevic T, et al. Antibiotic use in eastern Europe: A cross-national database study in coordination with the WHO Regional Office for Europe. Lancet Infect Dis 2014;14:381-7. https://doi.org/10.1016/S1473- 3099(14)70071-4
- 5. Isler B, Keske Ş, Aksoy M, Azap Ö, Yilmaz M, Yavuz S, et al. Antibiotic overconsumption and resistance in Turkey. Clin Microbiol Infect 2019;25:651-3. https://doi.org/10.1016/j.cmi.2019.02.024
- 6. Aksoy M, Alkan A, Isli F. Rational drug use promotional activities of Ministry of Health. Turkiye Klinikleri J Pharmacol Special Topics 2015;3:19-26.
- 7. Aydingöz Se, Lux Km. Evaluation of antibiotic consumption of populatıion and antibiotic prescribing practices in primary health care services in Turkey in comparison to OECD countries. J Health Sci 30:56-62. https://doi. org/10.34108/eujhs.808230
- 8. Türkiye İstatistik Kurumu (TÜİK). Dünya nüfus günü, 2022. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Dunya-Nufus-Gunu-2022-45552 (Accessed date: 06.07.2022).
- 9. Raosoft Inc. (2004) RaoSoft® sample size calculator. Available from: http://www.raosoft.com/samplesize.html (Accessed date: 05.03.2021).
- 10. U.S. Agency for International Development, Management Sciences for Health, Macro International Inc. Antimicrobial resistance module for population-based surveys, Demographic and Health Survey. Washington: Management Sciences for Health & Macro International Inc; 2008.
- 11. Nepal A, Hendrie D, Robinson S, Selvey LA. Knowledge, attitudes and practices relating to antibiotic use among community members of the Rupandehi District in Nepal. BMC Public Health 2019;19:1-12. https://doi.org/10.1186/ s12889-019-7924-5
- 12. Yusef D, Babaa AI, Bashaireh AZ, Al-Bawayeh HH, Al-Rijjal K, Nedal M, et al. Knowledge, practices & attitude toward antibiotics use and bacterial resistance in Jordan: A cross-sectional study. Infect Dis Health 2018;23:33-40. https://doi.org/10.1016/j.idh.2017.11.001
- 13. Awad AI, Aboud EA. Knowledge, attitude and practice towards antibiotic use among the public in Kuwait. PloS One 2015;10:e0117910. https://doi.org/10.1371/journal.pone.0117910
- 14. Azap A, Akın TO, Başçavuş M, Ercan E, Kuşçu DD, Namal İ, et al. Public knowledge and attitudes regarding antibiotic use in Ankara, Turkey. Infect Dis Clin Microbiol 2019;1:134- 43. https://doi.org/10.36519/idcm.2019.19025
- 15. Korkut Y, Alime E, Ayada C. Evaluation of the knowledge, attitudes, and behaviors of antibiotics usage at the parents living in the aegean part of Turkey. Konuralp Med J 2019;11:350-5. https://doi.org/10.18521/ktd.530416
- 16. Gül S, Öztürk DB, Yılmaz MS, Uz Gül E. Evaluation of public knowledge and attitudes regarding self medication with antibiotics in Ankara. Turk Bull Hyg Exp Biol 2014;71:107-12. https://doi.org/10.5505/TurkHijyen.2014.60024
- 17. Yiğit M, Karagöl C. An examination of parental knowledge and attitudes about the rational use of antibiotics. Int J Gen Med 2022;32:287-92. https://doi.org/10.54005/geneltip.1096837
- 18. Albayrak A, Karakaş NM, Karahalil B. Evaluation of parental knowledge, attitudes and practices regarding antibiotic use in acute upper respiratory tract infections in children under 18years of age: A cross-sectional study in Turkey. BMC Pediatr 2021;21:554. https://doi.org/10.1186/ s12887-021-03020-4
- 19. Tshokey T, Adhikari D, Tshering T, Wangmo S, Wangdi K. Assessing the knowledge, attitudes, and practices on antibiotics among the general public attending the outpatient pharmacy units of hospitals in Bhutan: A cross-sectional survey. Asia Pac J Public Health 2017;29:580-8. https:// doi.org/10.1177/1010539517734682
- 20. André M, Vernby Å, Berg J, Lundborg CS. A survey of public knowledge and awareness related to antibiotic use and resistance in Sweden. J Antimicrob Chemother 2010;65:1292-6. https://doi.org/10.1093/jac/dkq104
- 21. Gillani AH, Chang J, Aslam F, Saeed A, Shukar S, Khanum F, et al. Public knowledge, attitude, and practice regarding antibiotics use in Punjab, Pakistan: A cross-sectional study. Expert Rev Anti Infect Ther 2021;19:399-411. https://doi. org/10.1080/14787210.2021.1823216
- 22. Oh AL, Hassali MA, Al-Haddad MS, Sulaiman SAS, Shafie AA, Awaisu A. Public knowledge and attitudes towards antibiotic usage: A cross-sectional study among the general public in the state of Penang, Malaysia. J Infect Dev Ctries 2011;5:338-47. https://doi.org/10.3855/jidc.1502
- 23. McNulty CA, Boyle P, Nichols T, Clappison P, Davey P. Don’t wear me out-the public’s knowledge of and attitudes to antibiotic use. J Antimicrob Chemother 2007;59:727-38. https://doi.org/10.1093/jac/dkl558
- 24. Abu Taha A, Abu-Zaydeh A, Ardah R, Al-Jabi S, Sweileh W, Awang R, et al. Public knowledge and attitudes regarding the use of antibiotics and resistance: Findings from a cross-sectional study among Palestinian adults. Zoonoses Public Health 2016;63:449-57. https://doi.org/10.1111/ zph.12249
- 25. Lopez-Vazquez P, Vazquez-Lago JM, Figueiras A. Misprescription of antibiotics in primary care: A critical systematic review of its determinants. J Eval Clin Pract 2012;18:473- 84. https://doi.org/10.1111/j.1365-2753.2010.01610.x
- 26. Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: Qualitative study of general practitioners’ and patients’ perceptions of antibiotics for sore throats. BMJ 1998;317:637-42. https://doi. org/10.1136/bmj.317.7159.637
- 27. Ong S, Nakase J, Moran GJ, Karras DJ, Kuehnert MJ, Talan DA, et al. Antibiotic use for emergency department patients with upper respiratory infections: Prescribing practices, patient expectations, and patient satisfaction. Ann Emerg Med 2007;50:213-20. https://doi.org/10.1016/j.annemergmed.2007.03.026
- 28. Sa’ed HZ, Taha AA, Araj KF, Abahri IA, Sawalha AF, Sweileh WM, et al. Parental knowledge, attitudes and practices regarding antibiotic use for acute upper respiratory tract infections in children: A cross-sectional study in Palestine. BMC Pediatr 2015;15:1-9. https://doi.org/10.1186/ s12887-015-0494-5
- 29. Mazi-ska B, Stru-ycka I, Hryniewicz W. Surveys of public knowledge and attitudes with regard to antibiotics in Poland: Did the European Antibiotic Awareness Day campaigns change attitudes? PloS One 2017;12:e0172146. https://doi.org/10.1371/journal.pone.0172146
- 30. Kusama Y, Tsuzuki S, Muraki Y, Koizumi R, Ishikane M, Ohmagari N. The effects of Japan’s National Action Plan on Antimicrobial Resistance on antimicrobial use. Int J Infect Dis 2021;103:154-6. https://doi.org/10.1016/j. ijid.2020.11.158
- 31. Gu Y, Fujitomo Y, Ohmagari N. Outcomes and future prospect of Japan’s national action plan on antimicrobial resistance (2016-2020). Antibiotics 2021;10:1293. https:// doi.org/10.3390/antibiotics10111293
- 32. Ivanovska V, Angelovska B, Van Dijk L, Zdravkovska M, Leufkens HG, Mantel-Teeuwisse AK. Change in parental knowledge, attitudes and practice of antibiotic use after a national intervention programme. Eur J Public Health 2018;28:724-9. https://doi.org/10.1093/eurpub/ckx240
- 33. Demoré B, Mangin L, Tebano G, Pulcini C, Thilly N. Public knowledge and behaviours concerning antibiotic use and resistance in France: A cross-sectional survey. Infection 2017;45:513-20. https://doi.org/10.1007/s15010-017- 1015-2
- 34. Belongia EA, Naimi TS, Gale CM, Besser RE. Antibiotic use and upper respiratory infections: A survey of knowledge, attitudes, and experience in Wisconsin and Minnesota. Prev Med 2002;34:346-52. https://doi.org/10.1006/ pmed.2001.0992
- 35. You J, Yau B, Choi K, Chau C, Huang Q, Lee S. Public knowledge, attitudes and behavior on antibiotic use: A telephone survey in Hong Kong. Infection 2008;36:153-7. https:// doi.org/10.1007/s15010-007-7214-5
- 36. Waaseth M, Adan A, Røen IL, Eriksen K, Stanojevic T, Halvorsen KH, et al. Knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers-a cross-sectional study. BMC Public Health 2019;19:1-12. https://doi.org/10.1186/s12889-019-6409-x
- 37. Vallin M, Polyzoi M, Marrone G, Rosales-Klintz S, Tegmark Wisell K, Stålsby Lundborg C. Knowledge and attitudes towards antibiotic use and resistance-a latent class analysis of a Swedish population-based sample. PloS One 2016;11:e0152160. https://doi.org/10.1371/journal.pone.0152160
- 38. Hernández-Díaz I, Ayala-Meléndez A, González-González E, Rosario-Calderón I, Figueroa-Ríos D, Melin K, et al. Knowledge and beliefs, behaviors, and adherence among Latino parents or legal guardians related to antibiotic use for upper respiratory tract infections in children under 6 years of age. J Am Pharm Assoc 2019;59:506-13. https://doi. org/10.1016/j.japh.2019.03.004
- 39. Türkiye İstatistik Kurumu (TÜİK). Türkiye istatistikleri, 2020. Available from: https://www.tuik.gov.tr/media/announcements/turkiye_istatistikleri_2020.pdf.
- 40. Türkiye İstatistik Kurumu (TÜİK). Hanehalkı bilişim teknolojileri (BT) kullanım araştırması, 2021. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Hanehalki-Bilisim-Teknolojileri-(BT)-Kullanim-Arastirmasi-2021 (Accessed date: 26.09.2021).
| APA | Karahalil B, Albayrak A, Ozger H (2023). Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. , 341 - 352. 10.5578/flora.20239704 |
| Chicago | Karahalil Bensu,Albayrak Aslınur,Ozger H.Selcuk Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. (2023): 341 - 352. 10.5578/flora.20239704 |
| MLA | Karahalil Bensu,Albayrak Aslınur,Ozger H.Selcuk Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. , 2023, ss.341 - 352. 10.5578/flora.20239704 |
| AMA | Karahalil B,Albayrak A,Ozger H Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. . 2023; 341 - 352. 10.5578/flora.20239704 |
| Vancouver | Karahalil B,Albayrak A,Ozger H Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. . 2023; 341 - 352. 10.5578/flora.20239704 |
| IEEE | Karahalil B,Albayrak A,Ozger H "Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey." , ss.341 - 352, 2023. 10.5578/flora.20239704 |
| ISNAD | Karahalil, Bensu vd. "Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey". (2023), 341-352. https://doi.org/10.5578/flora.20239704 |
| APA | Karahalil B, Albayrak A, Ozger H (2023). Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 28(3), 341 - 352. 10.5578/flora.20239704 |
| Chicago | Karahalil Bensu,Albayrak Aslınur,Ozger H.Selcuk Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 28, no.3 (2023): 341 - 352. 10.5578/flora.20239704 |
| MLA | Karahalil Bensu,Albayrak Aslınur,Ozger H.Selcuk Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, vol.28, no.3, 2023, ss.341 - 352. 10.5578/flora.20239704 |
| AMA | Karahalil B,Albayrak A,Ozger H Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2023; 28(3): 341 - 352. 10.5578/flora.20239704 |
| Vancouver | Karahalil B,Albayrak A,Ozger H Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2023; 28(3): 341 - 352. 10.5578/flora.20239704 |
| IEEE | Karahalil B,Albayrak A,Ozger H "Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey." Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 28, ss.341 - 352, 2023. 10.5578/flora.20239704 |
| ISNAD | Karahalil, Bensu vd. "Public Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance in Türkiye: A Cross-Sectional Survey". Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 28/3 (2023), 341-352. https://doi.org/10.5578/flora.20239704 |
