Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

AKDAĞ, Alper; ALTINTAS, ENGIN; Ozdogan, Osman; Sezgin, Orhan; Abaylı, Bahri; GÖZÜKÜÇÜK, Süveyda; MIDIKLI, Dürdane; Ucbilek, Enver; KOYUNCU, MAHMUT BAKIR

Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

Enver ÜÇBİLEK, (Mersin Üniversitesi Tıp Fakültesi, Gastroenteroloji Bölümü, Mersin, Türkiye)

Bahri ABAYLI, (Dr. Aşkım Tüfekçi Devlet Hastanesi, Çukurova Gastroenteroloji Bölümü, Adana, Türkiye)

Mahmut Bakır KOYUNCU, (Mersin Üniversitesi Tıp Fakültesi, Gastroenteroloji Bölümü, Mersin, Türkiye)

Dürdane MIDIKLI, (Adana Devlet Hastanesi, İnfeksiyon Hastalıkları Anabilim Dalı, Adana, Türkiye)

Süveyda GÖZÜKÜÇÜK, (Dr. Ekrem Tok Psikiyatri Hastanesi, Enfeksiyon Hastalıkları Anabilim Dalı, Adana, Türkiye)

Alper AKDAĞ, (Ceyhan Devlet Hastanesi Enfeksiyon Hastalıkları Anabilim Dalı, Adana, Türkiye)

Osman ÖZDOĞAN, (Tarsus Devlet Hastanesi Gastroenteroloji Bölümü, Mersin, Türkiye)

Engin ALTINTAŞ, (Mersin Üniversitesi Tıp Fakültesi, Gastroenteroloji Bölümü, Mersin, Türkiye)

Orhan SEZGİN (Mersin Üniversitesi Tıp Fakültesi, Gastroenteroloji Bölümü, Mersin, Türkiye)

Turkish Journal of Medical Sciences

3 0

Yıl: 2016 Cilt: 46 Sayı: 1 Sayfa Aralığı: 66 - 71 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

Öz:

Background/aim: The most common hepatitis C virus (HCV) genotype in Turkey is genotype 1. However, there has not been a study about the distribution of HCV genotypes among intravenous drug users (IVDUs) in the Çukurova region of Turkey. This study was planned to understand if there is a difference between IVDUs and the normal population. Materials and methods: Between May 2010 and May 2014, anti-HCV positive IVDUs who applied to the 6 hospitals in the Çukurova region of Turkey were included in this study. Their HCV genotypes were studied. Results: Ninety-seven anti-HCV positive IVDUs were screened in terms of HCV RNA and genotype. Ten were excluded from the study because their HCV RNA results were negative. Fifty-one of the 87 patients (58.6%) had genotype 3. Genotype 2 was detected in 26 (29.9%) and genotype 1 was detected in 10 (11.5%) patients. Conclusion: HCV genotypes seem to be different between the normal population and IVDUs according to studies worldwide. Among IVDUs, we detected a dominance of genotype 3 and genotype 2, which is apparently different from the normal population. The reason for this difference can be simply explained by infection through shared needles. However, there may still be a different immunological response in IVDUs, the investigation of which may lead to further studies.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ucbilek E, Abaylı B, KOYUNCU M, MIDIKLI D, GÖZÜKÜÇÜK S, AKDAĞ A, Ozdogan O, ALTINTAS E, Sezgin O (2016). Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. , 66 - 71.
Chicago	Ucbilek Enver,Abaylı Bahri,KOYUNCU MAHMUT BAKIR,MIDIKLI Dürdane,GÖZÜKÜÇÜK Süveyda,AKDAĞ Alper,Ozdogan Osman,ALTINTAS ENGIN,Sezgin Orhan Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. (2016): 66 - 71.
MLA	Ucbilek Enver,Abaylı Bahri,KOYUNCU MAHMUT BAKIR,MIDIKLI Dürdane,GÖZÜKÜÇÜK Süveyda,AKDAĞ Alper,Ozdogan Osman,ALTINTAS ENGIN,Sezgin Orhan Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. , 2016, ss.66 - 71.
AMA	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. . 2016; 66 - 71.
Vancouver	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. . 2016; 66 - 71.
IEEE	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O "Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey." , ss.66 - 71, 2016.
ISNAD	Ucbilek, Enver vd. "Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey". (2016), 66-71.

APA	Ucbilek E, Abaylı B, KOYUNCU M, MIDIKLI D, GÖZÜKÜÇÜK S, AKDAĞ A, Ozdogan O, ALTINTAS E, Sezgin O (2016). Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. Turkish Journal of Medical Sciences, 46(1), 66 - 71.
Chicago	Ucbilek Enver,Abaylı Bahri,KOYUNCU MAHMUT BAKIR,MIDIKLI Dürdane,GÖZÜKÜÇÜK Süveyda,AKDAĞ Alper,Ozdogan Osman,ALTINTAS ENGIN,Sezgin Orhan Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. Turkish Journal of Medical Sciences 46, no.1 (2016): 66 - 71.
MLA	Ucbilek Enver,Abaylı Bahri,KOYUNCU MAHMUT BAKIR,MIDIKLI Dürdane,GÖZÜKÜÇÜK Süveyda,AKDAĞ Alper,Ozdogan Osman,ALTINTAS ENGIN,Sezgin Orhan Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. Turkish Journal of Medical Sciences, vol.46, no.1, 2016, ss.66 - 71.
AMA	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. Turkish Journal of Medical Sciences. 2016; 46(1): 66 - 71.
Vancouver	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey. Turkish Journal of Medical Sciences. 2016; 46(1): 66 - 71.
IEEE	Ucbilek E,Abaylı B,KOYUNCU M,MIDIKLI D,GÖZÜKÜÇÜK S,AKDAĞ A,Ozdogan O,ALTINTAS E,Sezgin O "Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey." Turkish Journal of Medical Sciences, 46, ss.66 - 71, 2016.
ISNAD	Ucbilek, Enver vd. "Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey". Turkish Journal of Medical Sciences 46/1 (2016), 66-71.