Aim: The aim of this study was to examine the coping with stress styles of nursing students and the factors that affect them. Method: The study employed a cross-sectional research design. The data of the study were collected from students in the Health Science Faculty Nursing Department of a university at the Lefkoşe between January and April 2015. The sample of the study consisted of 228 students. The sample size calculation formula for known populations was used to determine the sample. Later, the sample size was stratified in accordance with classes. A student identification form and the Stress-Coping Styles Scale were used as data collection tools. Results: The students in their final year of study had higher self-confident approach subscale score average of the Stress-Coping Styles Scale than those in other years of study. The mean subscale scores of students in their third and fourth years of study in all subdimensions were higher than those of students in their first year of study. The social support seeking behavior mean subscale score average of female students was found to be higher, while the scores of students who were smokers were higher in the unconfidence, submissive approach and seeking social support approach subdimensions. The unconfidence scores of students who were not using alcohol were found to be lower, while their social support seeking behavior subscale scores average were higher. The unconfidence subscale scores average of students who were living in homes alone or with their friends were higher than those residing in dormitories. This study also found that self-confident approach, optimistic approach and unconfidence subscale scores average of students who had failed any years of school were higher. Conclusion: This study found that year of study, gender, smoking and alcohol intake, residence and having failed any years of school affected the coping with stress styles of students.