Aim: This study aims to explore the relationship between the university students smoking behavior and coping formats with stress and loneliness. Material and Methods: The sample of the study consists of 712 students that study at different departments of Balıkesir University. Research data were collected via personal information form, UCLA Loneliness Scale and Styles of Coping with Stress Scale. Findings: In this study it is found that in comparison to female students, male students smoke at a higher rate. It is found that there is a statistically significant difference according to the students' age group in terms of smoking behaviour and students 21 years old and older than 21 are more likely to smoke (p<0.05). When it is examined according to mothers' working status and smoking behavior It is found that the students whose mothers are employed smoke at a higher rate than the students whose mothers are unemployed. It is determined that non smoker students' social support subscale point average of Stress Coping Styles Inventory is higher than smoker students (p<0.05).Results: It is found out that there is no significant difference statistically between smoker and non smoker students' average points of loneliness and subscales of Styles of Coping with Stress Scale (p> 0.05). Only non-smoking students social support seeking behavior is detected at higher rate in comparison to smoking students. It is considered that conducting new studies related with smoking behavior in more detail will useful.