Objective: The aim of this study was to evaluate the drug utilization by elderly patients over 65 years of age and provide information on polypharmacy.Methods: A single-center, retrospective study was conducted using the medical records of elderly patients (>=65 years of age) who were admitted to the Doganlar Family Health Center in Izmir between January 2013 and December 2013. Demographic characteristics of patients, diagnoses, frequency of health care contacts and prescribed drugs were evaluated. Results: A total of 218 elderly patients (122 female, 96 male) attending the health center were included in the study. Mean ages of the male, and female patients were 75.52±5.4, and 74.71±5.6 years, respectively. Nearly half of the patients were illiterate, and most of them were female. The most common chronic diseases were hypertension (48.1%), coronary artery disease (27.0%), diabetes mellitus (23.2%), respiratory disease (17.2%) and hyperlipidemia (12.8%). Polypharmacy was observed among elderly patients. While 17.8% of the patients were not using their medications regularly, they were using one drug (10.5%), two (13.7%), three (11.3%), four (8.7%), five or more than five drugs, concomitantly. Symptomatic treatment was very frequently used, one in two patients took at least one proton pump inhibitor or nonsteroidal antiinflammatory drug (more frequent among female patients, p<0.05). Conclusion: Our data have demonstrated that polypharmacy was quiet widely used by elderly patients. The effects and interactions of the drugs used concomitantly should be carefully evaluated before starting treatment in the elderly. Further studies focusing on drug use in elderly will be able to increase the success rates in geriatric pharmacotherapy.