Aim: This study was carried out in order to evaluate the attitudes and behaviors of student nurses towards care-focused interaction of nurse-patient. Method: This descriptive study was conducted with 258 students studying in nursing department of Faculty of Health Sciences during 2016-2017 school year. As data collection tools, “Personal Information Form” and “Care-Focused Nurse-Patient Interaction Scale” (CFNPIS) were used. In the analysis of the data, significance test of difference between the two means, variance analysis and Mann Whitney U test were used. Results: It was found out that, there is no relationship between the ages of the students and the subdimensions of “importance”, “adequacy” and “applicability”of care-focused patient-nurse interaction scale and there is a meaningful difference among their average scores in “importance” subdimension according to their gender and grade; “adequacy” subdimension according to their social activities; “importance, adequacy and applicability”subdimensions according tothe reasons of choosing nursing profession; “importance, adequacy and applicability” subdimensions according to their perception of care as the basic duty of nurses; “importance, adequacy and applicability” subdimensions according to their difficulty experiences in their internship (p<0.05). Conclusion: As a result, it was found that student nurses have positive attitudes and behaviors towards care-oriented nurse-patient interactions and the female nurse students who studies in the last grade, who chose nursing occupation due to their love for the occupation, who believe care is the core responsibility of a nurse, who do not experience difficulties in their communication with the patients during their internship have more positive attitudes and behaviors in care-oriented nurse-patient interaction.