The present study focuses on the psychological reflections of the concept of ‘tawakkul,’ which can be roughly translated as, after doing everything within one’s willpower, putting his trust in God and fully accepting whatsoever comes from Him. The very essence of tawakkul is submitting one’s self to the will power and discretion of God and appreciating His decree. When man attempts to command and regulate time, events, people, or things he is immediately confronted with the harsh reality of his impotency and powerlessness. Thus, he starts feeling weak, helpless, and out of control. The state of such feelings may lead to certain psychological troubles such as fear, hopelessness, and depression. In order to cope with such negative moods of tension and inner paradoxes, man is in great need of social, emotional, and spiritual support. At this point, tawakkul can be an important spiritual support system to help man regain the sense of control and hope and relive stress that steams from anxiety. Tawakkul helps man reduce his levels of anxiety by submitting his ultimate powerlessness to the One Who is ultimately powerful; his ultimate destitute to the One Who is the most generous; and his fear of uncertainty of the future to the One Who owns the time. In the most general sense, tawakkul is the main constituent of peace, tranquility, and serenity. It is asserted that tawakkul leads to significant decrease in the levels of anxiety and depression. Through tawakkul, human suffering is transformed into infinite strength, the ultimate poverty into limitless wealth, the uncertainty of the future into crystal clarity. As a result, human mind in the most general sense finds serenity. The present study investigated why man needs tawakkul, wisdom behind tawakkul, and the psychological reflections of tawakkul at the individual level. The study reviewed the relevant literature. More specifically, the importance and reflections of tawakkul is discussed in the light of the 173th verse of the Holy Quran. The review of religious and psychological literature showed that tawakkul, is a spiritual feeling that develops on the basis of the belief that Allah is the creator and the creator of all that exists in the universe, brings man to the top with a sense of trust, a guarantee of psychological soundness, and is a positive coping strategy that relieves damaging emotions in man. Tawakkul saves man from the fear of eternal non-existence and gives the hope of eternal life. It becomes a point of support against the situations and events that man does not have any control over. In addition, it also becomes a support point in satisfying endless needs that man does not have any way of satisfying. Tawakkul connects man to his creator and saves him from loneliness. Another positive effect of tawakkul is that it helps man find the meaning of his life which gives him psychological comfort and resilience. In this sense, trust in God is considered as a route to power and wealth for powerless and poor man.