Yıl: 2020 Cilt: 83 Sayı: 1 Sayfa Aralığı: 17 - 22 Metin Dili: İngilizce DOI: 10.26650/IUITFD.2019.0031 İndeks Tarihi: 27-04-2020

PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE

Öz:
Objective: To evaluate the outcomes of pregnancies with maternalheart disease.Material and Method: The results of 115 patients in our clinicbetween 2013 and 2018 were retrospectively analyzed. The typeof heart disease and functional classification of the New YorkHeart Association were taken into consideration when evaluatingthe cases.Results: According to the New York Heart Association classification,the distribution of patients was 67.1% for stage I, 18.2%for stage II, and 14.7% for stage III–IV. There was no maternalor perinatal mortality. The incidence of rheumatic and congenitalheart diseases was 51.3% and 27.8%, respectively. Maternalmorbidity was observed in 18 cases (15.6%). Mean gestationalage and birth weight were significantly higher in the stage I–IIfunctional capacity group (p<0.001). Maternal morbidity and admissionrates to neonatal intensive care unit were significantlyhigher in the stage III–IV functional capacity group (p<0.001).There was no significant difference between stage I–II and stageIII–IV groups in terms of cesarean delivery rates and fetal growthrestriction (p>0.05).Conclusion: It is possible to obtain satisfactory results for bothmother and fetus in the majority of pregnant women with heartdisease when managed with a multidisciplinary approach.
Anahtar Kelime:

MATERNAL KALP HASTALIĞI OLAN 115 GEBELİK OLGUSUNUN SONUÇLARI

Öz:
Amaç: Maternal kalp hastalığı bulunan gebeliklerin sonuçlarını değerlendirmek. Gereç ve Yöntem: 2013-2018 yılları arasında bir kliniğimizdeki 115 maternal kalp hastalığı olan olgunun sonuçları retrospektif olarak incelenmiştir. Olgular değerlendirilirken kalp hastalıklarının türü ve New York Kalp Derneği’nin fonksiyonel sınıflaması göz önünde bulundurulmuştur. Bulgular: New York Kalp Derneği sınıflamasına göre hastaların dağılımı evre I için %67,1, evre II için %18,2, evre III–IV için ise %14,7 idi. Maternal ya da perinatal mortalite saptanmadı. Romatizmal ve konjenital kalp hastalıklarının görülme oranı sırasıyla %51,3 ve %27,8 olarak bulundu. Maternal morbidite 18 olguda (%15,6) gözlendi. Ortalama doğum haftası ve doğum kilosu evre I–II fonksiyonel kapasiteli grupta belirgin yüksekti (p<0,001). Maternal morbidite ve yenidoğan yoğun bakım ünitesine kabul oranları ise evre III–IV fonksiyonel kapasiteli grupta belirgin yüksekti (p<0,001). Evre I–II ve evre III–IV grupları arasında sezeryan ile doğum oranları ve fetal gelişim kısıtlılığı görülme sıklığı açısından anlamlı fark saptanmadı (p>0,05). Sonuç: Multidisipliner bir yaklaşımla yönetildiğinde kalp hastalığı bulunan gebelerin çoğunluğunda hem anne hem fetüs için memnun edici sonuçların alınması mümkündür.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Cantwell R, Clutton-Brock T, Cooper G, Dawson A, Drife J, Garrod D, et al. Saving Mothers’ Lives: reviewing maternal deaths to make motherhood safer: 2006-2008. The eighth report of the confidential enquiries into maternal deaths in the United Kingdom. BJOG. 2011;118(suppl 1):1-203. [CrossRef]
  • 2. Elkayam U, Goland S, Pieper PG, Silverside CK. High- risk cardiac disease in pregnancy: part I. J Am Coll Cardiol 2016;68:396-410. [CrossRef]
  • 3. JCS Joint Working Group Guidelines for indication and management of pregnancy and delivery in women with heart dis- ease (JCS 2010): digest version. Circ J 2012;76:240- 60. [CrossRef]
  • 4. Lima FV, Yang J, Xu J, Stergiopoulos K. National trends and in-hospital outcomes in pregnant women with heart disease in the United States. Am J Cardiol 2017;119:1694- 700. [CrossRef]
  • 5. Opotowsky AR, Siddiqi OK, Webb GD. Trends in hospitalizations for adults with congenital heart disease in the U.S. J Am Coll Cardiol 2009;54:460-7. [CrossRef]
  • 6. Owens A, Yang J, Nie L, Lima F, Avila C, Stergiopoulos K. Neonatal and Maternal Outcomes in Pregnant Women With Cardiac Disease J Am Heart Assoc 2018;7(21):e009395. [CrossRef]
  • 7. Ruys TP, Cornette J, Roos-Hesselink JW. Pregnancy and delivery in cardiac disease. J Cardiol 2013;61:107-12. [CrossRef]
  • 8. Hameed A, Karralp IS, Tummula PP,Wani OR, Canetti M, Akhter MW, et al.The effects of valvular heart disease on maternal and fetal outcome of pregnancy. J Am Coll Cardiol 2001;37:893-9. [CrossRef]
  • 9. The Criteria Committee of the New York Heart Association. Nomenclature and criteria for diagnosis of diseases of the heart and great vessels, 8th ed. New York: Heart Association; 1979.
  • 10. Roos-Hesselink JW, Ruys TP, Stein JI, Thilen U, Webb GD, Niwa K, et al. ROPACInvestigators. Outcome of pregnancy in patients with structural or ischaemicheart disease: results of a registry ofthe European Society of Cardiology. Eur Heart J 2013;34(9):657-65. [CrossRef]
  • 11. Madazli R, Sal V, Cift T, Guralp O, Goymen A. Pregnancy outcomes in women with heart disease.Arch Gynecol Obstet 2010;281(1):29-34. [CrossRef]
  • 12. Abdel-Hady ES, El Shamy M, El Rifai AA, Goda H, Abdel- Samad A, Moussa S, et al. Maternal and perinatal outcome of pregnancies complicated by cardiac disease. Int J Gynaecol Obstet 2005;90:21-5. [CrossRef]
  • 13. Bhatla N, Lal S, Behera GKriplani A, Mittal S, Agarwal N, et al. Cardiac disease in preg- nancy. Int J Gynaecol Obstet 2003;82:153-9. [CrossRef]
  • 14. Avila WS, Rossi EG, Ramires JA, Grinberg M, Bortolotto MR, Zugaib M, et al. Pregnancy in patients with heart disease: experience with 1,000 cases. Clin Cardiol 2003;26:135-42. [CrossRef]
  • 15. Köşüş A, Köşüş N, Açıkgöz N, Çapar M. Is there any difference between pregnancy with cardiac disease and normal pregnancy for maternal and fetal outcomes? Genel Tıp Derg 2008;18(2):55-60.
  • 16. Thompson JL, Kuklina EV, Bateman BT, Callaghan WM, James AH, Grotegut CA. Medical and Obstetric Outcomes Among Pregnant Women With Congenital Heart Disease. Obstet Gynecol 2015;126(2): 346-54. [CrossRef]
  • 17. Aggarwal N, Suri V, Kaur H, Chopra S, Rohila M, Vijayvergia R. Retrospective analysis of outcome of pregnancy in women with congenital heart disease: single-centre experience from North India. Aust N Z J Obstet Gynaecol 2009;49:376-81. [CrossRef]
  • 18. Sidlik R, Sheiner E, Levy A, Wiznitzer A. Effect of maternal congenital heart defects on labor and delivery outcome: a population-based study. J Matern Fetal Neonatal Med 2007;20:211-6. [CrossRef]
  • 19. Koregol M, Mahale N, Nayak R, Bhandary A. Maternal and perinatal outcomes of pregnancies complicated by cardiac disease. J Turkish-German Gynecol Assoc 2009;10:30-4.
  • 20. Subbaiah M, Sharma V, Kumar S, Rajeshwari S, Kothari SS, Roy KK, et al. Heart disease in pregnancy: cardiac and obstetric outcomes. Arch Gynecol Obstet 2013;288:23-7. [CrossRef]
  • 21. Siu SC, Colman JM, Sorensen S, Smallhorn JF, Farine D, Amankwah KS, et al. Adverse Neonatal and cardiac outcomes are more common in Pregnant women with cardiac disease. Circulation 2002;105(18):2179-84. [CrossRef]
  • 22. Wenstrom Katharine D. Protocol 15 Cardiac Disease. In: Queenan JT, Spong CY, Lockwood CJ, eds. Protocols for High-Risk Pregnancies An Evidence-Based Approach. 6th ed. Willey Blackwell; 2015. p. 128-139. [CrossRef]
  • 23. Davutoglu E, Yuksel MA, Oncul M, Cebi S, Madazli R. Heart disease and pregnancy: Maternal and fetal otcomes. Turkiye Klinikleri J Gynecol Obst 2015;25(2):103- 10. [CrossRef]
APA Ozel A, HAMZAOĞLU K, Durmaz E, Madazli R (2020). PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. , 17 - 22. 10.26650/IUITFD.2019.0031
Chicago Ozel Aysegul,HAMZAOĞLU Kübra,Durmaz Eser,Madazli Riza PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. (2020): 17 - 22. 10.26650/IUITFD.2019.0031
MLA Ozel Aysegul,HAMZAOĞLU Kübra,Durmaz Eser,Madazli Riza PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. , 2020, ss.17 - 22. 10.26650/IUITFD.2019.0031
AMA Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. . 2020; 17 - 22. 10.26650/IUITFD.2019.0031
Vancouver Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. . 2020; 17 - 22. 10.26650/IUITFD.2019.0031
IEEE Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R "PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE." , ss.17 - 22, 2020. 10.26650/IUITFD.2019.0031
ISNAD Ozel, Aysegul vd. "PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE". (2020), 17-22. https://doi.org/10.26650/IUITFD.2019.0031
APA Ozel A, HAMZAOĞLU K, Durmaz E, Madazli R (2020). PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. İstanbul Tıp Fakültesi Dergisi, 83(1), 17 - 22. 10.26650/IUITFD.2019.0031
Chicago Ozel Aysegul,HAMZAOĞLU Kübra,Durmaz Eser,Madazli Riza PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. İstanbul Tıp Fakültesi Dergisi 83, no.1 (2020): 17 - 22. 10.26650/IUITFD.2019.0031
MLA Ozel Aysegul,HAMZAOĞLU Kübra,Durmaz Eser,Madazli Riza PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. İstanbul Tıp Fakültesi Dergisi, vol.83, no.1, 2020, ss.17 - 22. 10.26650/IUITFD.2019.0031
AMA Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. İstanbul Tıp Fakültesi Dergisi. 2020; 83(1): 17 - 22. 10.26650/IUITFD.2019.0031
Vancouver Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE. İstanbul Tıp Fakültesi Dergisi. 2020; 83(1): 17 - 22. 10.26650/IUITFD.2019.0031
IEEE Ozel A,HAMZAOĞLU K,Durmaz E,Madazli R "PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE." İstanbul Tıp Fakültesi Dergisi, 83, ss.17 - 22, 2020. 10.26650/IUITFD.2019.0031
ISNAD Ozel, Aysegul vd. "PREGNANCY OUTCOMES OF 115 CASES WITH MATERNAL HEART DISEASE". İstanbul Tıp Fakültesi Dergisi 83/1 (2020), 17-22. https://doi.org/10.26650/IUITFD.2019.0031