Aim: In this study, it was aimed to determine burnout, occupational satisfaction, depression symptom levels and sociodemographic characteristics affecting health personnel working in the operating room. Materials and Methods: The sample of the study consisted of a total of 230 people, including an anesthesiologist, a surgical nurse and an anesthesia technician working in the Erzurum Regional Training and Research Hospital and Atatürk University Medical Faculty Hospital. In the study, the Sociodemographic Data Form, Maslach Burnout Inventory , Minnesota Satisfaction Scale and Beck Depression Inventory were requested from participants Results: Emotional Exhaustion , Desensitization and Beck Depression Inventory scores were significantly higher and Personal Achievement scores were lower in operating room personnel working more than 60 hours a week (p <0.05). Desensitization scores were found to be significantly higher (p <0.05). Doctors' Emotional Exhaustion and Desensitization scores were high (p <0.05). There was a significant negative correlation between the Beck Depression Inventory and the Minnesota Satisfaction Scale and Personal Achievement scale scores of the employees; There was a significant positive correlation between the mean scores of the Emotional Exhaustion and Desensitization subscales (p <0.05) Conclusion: The operating room, which is a unit under intensive work pressure that requires effective, accurate and rapid intervention, will be useful in evaluating the mental health and working conditions of employees, reducing the work pressure and burden of employees and increasing the quality of service by increasing mental health and functioning.