Objectives: The present research was conducted to document the usage of medicinal plants, plant parts utilized, and methods of preparation by thepeople living in Aziziye district, situated in the western part of Erzurum.Materials and Methods: The medicinal plant species utilized by local public for remedial aims were collected and identified. The related knowledgeabout conventional herbal medicine was collected, herbarium materials were prepared, and they were deposited in the Herbarium of the Facultyof Science, Atatürk University.Results: A total of 77 medical plants pertaining to 30 families were defined in this research. Amongst these, 62 species grew naturally and 15species were cultivated. The most widespread medicinal plant families were Asteraceae (14), Rosaceae (7), Lamiaceae (5), and Apiaceae (5). Themost widespread preparation was decoction.Conclusion: The ethnobotanical outcomes documented in this study provide practical evidence about the use of medicinal plants among theinhabitants of Aziziye District. Furthermore, the results revealed that the medicinal plants of the region are a major source of herbal drugs forprimary healthcare utilized among the rural communities. This study can be utilized as baseline knowledge for further scientific research to improvenew plant-based commercial drugs, and may transfer the traditional information as regards usage of medicinal herbs to new generation.