Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery
Yıl: 2021 Cilt: 13 Sayı: 1 Sayfa Aralığı: 82 - 88 Metin Dili: İngilizce DOI: 10.18521/ktd.772556 İndeks Tarihi: 27-06-2021
Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery
Öz: Objective: The aim of this study was to compare the effectiveness of two preemptive sustained-release non-steroidal anti-inflammatory drugs in terms of pain, edema and trismus following third molar surgery.Methods: Overall, 30 patients with double-sided vertically positioned impacted third molars were included in this study. The study was randomized and double-blinded. 30 minutes before the surgery, patients were given sustained-release (SR) dexketoprofen trometamol 75 mg and following the surgery the drug administration continued postoperatively for 1 week, once a day. 2 weeks later, the same procedure was applied for the counterside impacted third molar with 75 mg. sustained-release (SR) diclofenac sodium. The pain was assessed postoperatively by VAS (Visual Analogue Scale) levels at the 6th, 8th, 12th, 24th and 48th hours and on the 3rd, 5th, and 7th days. Edema and trismus measurements were evaluated on the postoperative 2nd and 7th days.Results: There was a statistically significant difference between the groups in VAS levels at 6th, 8th, 12th, 24th, and 48th hours, and on the 3rd and 5th days (P <0.01). Dexketoprofen trometamol SR group had lower VAS levels than diclofenac sodium SR group. There was no statistically significant difference between the groups in terms of mean trismus and edema measurement on the 2nd and 7th days (P <0.05).Conclusions: Dexketoprofen trometamol SR and diclofenac sodium SR are similarly effective for the reduction of edema and trismus following impacted third molar surgery; however, dexketoprofen trometamol SR is found to be more efficient in reducing pain.
Anahtar Kelime: Preemptif Tek Doz Sürekli Salınımlı Non-steroid Antienflamatuar İlaçların Üçüncü Molar Cerrahisi Sonrası Postoperatif Komplikasyonlar Üzerine Etkileri
Öz: Amaç: Bu çalışmanın amacı, üçüncü molar cerrahisini takiben iki preemptif süreklisalınımlı nonsteroidal antienflamatuar ajanın ağrı, ödem ve trismus açısındanetkinliğini karşılaştırmaktır. Gereç ve Yöntem: Çift taraflı vertical pozisyonda gömülü üçüncü azı dişleri olan 30hasta çalışmaya dahil edildi. Çalışma randomize ve çift kör olarak planlandı.Ameliyattan 30 dakika önce hastalara 75 mg sürekli salınımlı (SR) deksketoprofentrometamol verildi ve ameliyat sonrası ilaç uygulaması günde bir kez olmak üzere 1hafta boyunca devam etti. 2 hafta sonra, 75 mg sürekli salınımlı (SR) diklofenaksodyum ile diğer gömülü üçüncü molar için aynı prosedür uygulandı. Ağrıpostoperatif 6., 8., 12., 24. ve 48. saatlerde ve 3., 5. ve 7. günlerde VAS (GörselAnalog Skala) ile değerlendirildi. Ödem ve trismus ölçümleri postoperatif 2. ve 7.günlerde gerçekleştirildi.Bulgular: 6., 8., 12., 24. ve 48. saatlerde ve 3. ve 5. günlerde VAS düzeylerindegruplar arasında istatistiksel olarak anlamlı bir fark bulundu (p <0.01).Deksketoprofen trometamol SR grubunun VAS düzeyleri, diklofenak sodyum SRgrubundan daha düşüktü. Gruplar arasında 2. ve 7. günlerde trismus ve ödem ölçümortalamaları açısından istatistiksel olarak anlamlı fark yoktu (p <0.05). Sonuç: Deksketoprofen trometamol SR ve diklofenak sodyum SR, gömülü üçüncümolar cerrahisini takiben ödem ve trismusun azaltılması için benzer şekilde etkilidir;bununla birlikte, deksketoprofen trometamol SR'nin ağrıyı azaltmada daha etkiliolduğu bulunmuştur.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Çebi A, Kasapoglu M (2021). Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. , 82 - 88. 10.18521/ktd.772556 |
| Chicago | Çebi Ahmet Taylan,Kasapoglu Metin Berk Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. (2021): 82 - 88. 10.18521/ktd.772556 |
| MLA | Çebi Ahmet Taylan,Kasapoglu Metin Berk Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. , 2021, ss.82 - 88. 10.18521/ktd.772556 |
| AMA | Çebi A,Kasapoglu M Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. . 2021; 82 - 88. 10.18521/ktd.772556 |
| Vancouver | Çebi A,Kasapoglu M Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. . 2021; 82 - 88. 10.18521/ktd.772556 |
| IEEE | Çebi A,Kasapoglu M "Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery." , ss.82 - 88, 2021. 10.18521/ktd.772556 |
| ISNAD | Çebi, Ahmet Taylan - Kasapoglu, Metin Berk. "Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery". (2021), 82-88. https://doi.org/10.18521/ktd.772556 |
| APA | Çebi A, Kasapoglu M (2021). Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. KONURALP TIP DERGİSİ, 13(1), 82 - 88. 10.18521/ktd.772556 |
| Chicago | Çebi Ahmet Taylan,Kasapoglu Metin Berk Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. KONURALP TIP DERGİSİ 13, no.1 (2021): 82 - 88. 10.18521/ktd.772556 |
| MLA | Çebi Ahmet Taylan,Kasapoglu Metin Berk Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. KONURALP TIP DERGİSİ, vol.13, no.1, 2021, ss.82 - 88. 10.18521/ktd.772556 |
| AMA | Çebi A,Kasapoglu M Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. KONURALP TIP DERGİSİ. 2021; 13(1): 82 - 88. 10.18521/ktd.772556 |
| Vancouver | Çebi A,Kasapoglu M Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery. KONURALP TIP DERGİSİ. 2021; 13(1): 82 - 88. 10.18521/ktd.772556 |
| IEEE | Çebi A,Kasapoglu M "Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery." KONURALP TIP DERGİSİ, 13, ss.82 - 88, 2021. 10.18521/ktd.772556 |
| ISNAD | Çebi, Ahmet Taylan - Kasapoglu, Metin Berk. "Effects of Preemptive Single Dose Sustained Release Non Steroidal Anti-Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery". KONURALP TIP DERGİSİ 13/1 (2021), 82-88. https://doi.org/10.18521/ktd.772556 |
