Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department

leylek, habip emrah; DURAK, VAHIDE ASLIHAN; koksal, ozlem

Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department

Habip Emrah LEYLEK, (Balıkesir Devlet Hastanesi, Balıkesir, Türkiye)

Vahide Aslıhan DURAK, (Uludağ Üniversitesi, Tıp Fakültesi, Acil Servis, Bursa, Türkiye)

Ozlem KOKSAL (Uludağ Üniversitesi, Tıp Fakültesi, Acil Servis, Bursa, Türkiye)

Anatolian Journal of Emergency Medicine

1 0

Yıl: 2020 Cilt: 3 Sayı: 4 Sayfa Aralığı: 111 - 116 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department

Öz:

Aim: Inflammatory mediators such as leukocyte count (WBC),neutrophil / lymphocyte ratio (NLR), platelet / lymphocyteratio(PLR), platelet distribution width (PDW) and C reactive protein(CRP) are used for the prediction of ischemic vascular events suchas acute coronary syndrome (ACS).In this study, the relationshipbetween inflammatory mediators and modifiable risk factors in thediagnosis of ACS and mortality was examined.Material and methods: A total of 100 patients with ST elevationmyocardial infarction (STEMI) and non-ST elevation myocardialinfarction (NSTEMI) were included in the study. Blood samples forWBC, neutrophil count, NLR, PLR, PDW and CRP and routine bloodlaboratory studies were taken at the time of admission of thepatients.Results: Of the patients diagnosed with ACS,49% was STEMIand 51% was NSTEMI. Female gender was found to be higher in theNSTEMI group than in the STEMI group and also the hypertensionratio was found to be higher in the NSTEMI group than in the STEMIgroup and it was found to be statistically significant. The NLRmedian value between the STEMI and NSTEMI diagnostic groupswas found to be higher in the NSTEMI group and statistically moresignificant.Conclusions: In conclusion; troponin, control troponin,lymphocyte and NLR ratio were found to be statistically significantbetween STEMI and NSTEMI diagnostic groups.In addition to this;age was found as an effective parameter on mortality.

Anahtar Kelime: leukocyte count platelet distribution width Acute coronary syndrome

Akut Koroner Sendromda Değiştirilebilir Risk Faktörleri ile Kan Hücresi Tipleri Arasındaki İlişki ve Acil Serviste Mortalite Tahmini

Öz:

Amaç: Lökosit sayısı (WBC), nötrofil / lenfosit oranı (NLR), trombosit / lenfosit oranı (PLR), trombosit dağılım genişliği (PDW) ve C reaktif protein (CRP) gibi inflamatuar medyatörler; akut koroner sendrom (AKS) gibi iskemik olayların tahmininde kullanılmaktadır. Çalışmamızda , AKS tanısında inflamatuar mediatörler , çeşitli risk faktörleri ve mortalite arasındaki ilişki incelenmiştir. Gereç ve Yöntem: Çalışmaya ST elevasyonlu miyokard enfarktüsü (STEMI) ve ST elevasyonu olmayan miyokard enfarktüsü (NSTEMI) tanısı olan toplam 100 hasta dahil edildi. Hastaların acile başvuru anındaki sırasında WBC, nötrofil sayımı, NLR, PLR, PDW,CRP değerleri ve diğer biokimyasal belirteçler için kan örnekleri alındı. Bulgular: AKS tanısı konan hastaların% 49'u STEMI ve% 51'i NSTEMI idi. Kadın cinsiyetin NSTEMI grubunda STEMI grubuna göre daha yüksek olduğu ve hipertansiyon oranının NSTEMI grubunda STEMI grubuna göre daha yüksek olduğu ve istatistiksel olarak anlamlı olduğu saptandı. STEMI ve NSTEMI tanı grupları arasındaki NLR medyan değeri, NSTEMI grubunda daha yüksek ve istatistiksel olarak daha anlamlı bulundu. Sonuç: Sonuç olarak; STEMI ve NSTEMI tanı grupları arasında troponin, kontrol troponin, lenfosit ve NLR oranının anlamlı farklılık gösterdiği bulunurken yaşın mortalite üzerinde etkili bir parametre olduğu görülmektedir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	leylek h, DURAK V, koksal o (2020). Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. , 111 - 116.
Chicago	leylek habip emrah,DURAK VAHIDE ASLIHAN,koksal ozlem Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. (2020): 111 - 116.
MLA	leylek habip emrah,DURAK VAHIDE ASLIHAN,koksal ozlem Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. , 2020, ss.111 - 116.
AMA	leylek h,DURAK V,koksal o Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. . 2020; 111 - 116.
Vancouver	leylek h,DURAK V,koksal o Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. . 2020; 111 - 116.
IEEE	leylek h,DURAK V,koksal o "Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department." , ss.111 - 116, 2020.
ISNAD	leylek, habip emrah vd. "Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department". (2020), 111-116.

APA	leylek h, DURAK V, koksal o (2020). Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine, 3(4), 111 - 116.
Chicago	leylek habip emrah,DURAK VAHIDE ASLIHAN,koksal ozlem Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine 3, no.4 (2020): 111 - 116.
MLA	leylek habip emrah,DURAK VAHIDE ASLIHAN,koksal ozlem Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine, vol.3, no.4, 2020, ss.111 - 116.
AMA	leylek h,DURAK V,koksal o Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine. 2020; 3(4): 111 - 116.
Vancouver	leylek h,DURAK V,koksal o Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department. Anatolian Journal of Emergency Medicine. 2020; 3(4): 111 - 116.
IEEE	leylek h,DURAK V,koksal o "Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department." Anatolian Journal of Emergency Medicine, 3, ss.111 - 116, 2020.
ISNAD	leylek, habip emrah vd. "Relationship Between Modifiable Risk Factors and Blood Cell Types in Acute Coronary Syndrome and Estimation of Mortality in Emergency Department". Anatolian Journal of Emergency Medicine 3/4 (2020), 111-116.