Objective: This study is to determine the factors which influence the quality of working life of nurses working at the hospital and the quality of working life. Method: As the population of the study comprised 1752 nurses working at public hospitals and a university hospital, its sample consisted of 315 nurses selected through stratified sampling according to the hospitals. Data was collected with information form, the scale of quality of working life in nursing, analyzed with ANOVA, t-test, correlation and regression test. Results: Of the nurses, 57.8% had undergraduate/postgraduate study, 77.1% of the nurses worked in the position 4A and 58.7 % of them worked at public hospitals. The total score was 2.85±0.46 which the nurses got from the scale of the quality of working life. Besides, the total scale points of the quality life of the nurses who had experiences within the rage 6-10 years, worked in internal and surgery services, were not satisfied with their job and the institution where they work, generally found the quality of working life bad and evaluate the relations manager and subordinate as a factor of the quality of working life were lower than the others and these findings were statistically significant. (p<0.05). Moreover, being unpleased especially with the institution worked (ß=-12.231), and with the job (ß=-7.136) which was one of these variables had a negative effect on the quality of working life of nurses. (F=35.379; p=0.000<0.05). Conclusion: The quality of working life of nurses was at medium level. Being unpleased especially with the institution worked and with nursing had a negative impact on the quality levels of working life of nurses.