Objective: This study was conducted to determine nursingstudents' attitudes and behaviors towards care-orientednurse-patient interaction. Method: The descriptive type of research was conducted withthe students of Bandırma Onyedi Eylül University, Faculty ofHealth Sciences, Department of Nursing in the 2017-2018Spring Semester in the 2nd, 3rd and 4th grade. Sampleselection was not used in the study, and the entire population(n=230) was included in the study. The research wascompleted with 210 students. Data were collected using thesociodemographic information form and the Care-OrientedNurse-Patient Interaction Scale. Permission to use the scalewas obtained from the researcher who developed the scale,written permission from the institution and verbal permissionfrom the students participating in the study. The analysisof the data was performed using the SPSS 25.0 statisticalprogram, number-percentage distributions, Mann-Whitney U,Kruskal Wallis, ANOVA tests. Results: The students' total mean scores for the dimensionof significance, adequacy, and applicability of Care-OrientedNurse-Patient Interaction Scale were found as 287.72±40.01,256.12±42.12 and 255.68±44.95, respectively. Importanceand sufficiency dimension according to the gender of thestudents; significance dimension according to the reason tochoose the nursing profession; importance, adequacy, andapplicability according to the situation of having difficultiesin relations with the patient; It was determined that there isa statistically significant difference between the total scoreaverages of applicability dimension according to the situationof having difficulties in social relations (p<0.05). The meanscores of the 2nd grade students for humanism, hope, helpfulrelationship, expression of feelings, problem solving andneeds sub-dimension were significantly higher than the othergrades (p<0.05). For the sensitivity sub-dimension of thirdgrade students, it was observed that the mean scores of thescale significance, competence and applicability levels weresignificantly higher than the mean scores of the second andfourth grade students (p<0.05). Conclusion: Students' attitudes and behaviors towards care oriented nurse-patient interaction were found to be positive.When planning nursing education, it can be suggestedthat student nurses develop the skills of taking a holisticapproach to the individual by interacting with the patientin a constructive and effective manner and not ignoring thespiritual dimension of care.