Frequency of glucose-6-phosphate dehydrogenase 
enzyme deficiency in newborns with prolonged jaundice

bozaykut, abdulkadir; taştanoğlu, hüseyin; Sezer Yamanel, Rabia Gönül

doi:10.14744/zkmj.2021.88709

Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice

Hüseyin TAŞTANOĞLU, (Sağlık Bilimleri Üniversitesi, Zeynep Kamil Annelik ve Çocuk Eğitimi ve Araştırma Hastanesi, Pediatri Anabilim Dalı, İstanbul, Türkiye)

Rabia Gönül SEZER YAMANEL, (Sağlık Bilimleri Üniversitesi, Zeynep Kamil Annelik ve Çocuk Eğitimi ve Araştırma Hastanesi, Pediatri Anabilim Dalı, İstanbul, Türkiye)

Abdülkadir BOZAYKUT (Sağlık Bilimleri Üniversitesi, Zeynep Kamil Annelik ve Çocuk Eğitimi ve Araştırma Hastanesi, Pediatri Anabilim Dalı, İstanbul, Türkiye)

Zeynep Kamil medical journal (Online)

6 3

Yıl: 2022 Cilt: 53 Sayı: 2 Sayfa Aralığı: 75 - 79 Metin Dili: İngilizce DOI: 10.14744/zkmj.2021.88709 İndeks Tarihi: 08-07-2022

Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice

Öz:

Objective: The aim of the study was to determine the frequency of glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency in preterm and term newborns with prolonged jaundice. Material and Methods: A total of 670 preterm and term newborns who applied to Zeynep Kamil Training and Research Hospital Pediatric Health Polyclinic with neonatal jaundice between January 1, 2014, and April 1, 2018, were retrospectively screened and included in the study. Birth weight, sex, gestational week, postnatal age, gender, phototherapy, and need for exchange transfusion were recorded. Laboratory evaluations included blood group typing of mother and newborn, serum total and direct bilirubin levels, reticulocyte count, and erythrocyte G6PD level. SPSS 22.0 was used as an evaluation program. Results: G6PD enzyme level was detected in 374 (55.8%) of the cases. Enzyme deficiency was detected in 12 (3.2%) cases. There was no statistically significant difference between the G6PD-deficient group and the G6PD-normal group in terms of all parameters except the total biluribin level. There was no case in whom exchange transfusion was performed with high bilirubin values. However, phototherapy was applied in 231 cases due to high bilirubin levels. It was determined that there was no need for phototherapy in all cases with G6PD levels. Conclusion: G6PD enzyme deficiency should be investigated in patients with prolonged jaundice.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	taştanoğlu h, Sezer Yamanel R, bozaykut a (2022). Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. , 75 - 79. 10.14744/zkmj.2021.88709
Chicago	taştanoğlu hüseyin,Sezer Yamanel Rabia Gönül,bozaykut abdulkadir Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. (2022): 75 - 79. 10.14744/zkmj.2021.88709
MLA	taştanoğlu hüseyin,Sezer Yamanel Rabia Gönül,bozaykut abdulkadir Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. , 2022, ss.75 - 79. 10.14744/zkmj.2021.88709
AMA	taştanoğlu h,Sezer Yamanel R,bozaykut a Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. . 2022; 75 - 79. 10.14744/zkmj.2021.88709
Vancouver	taştanoğlu h,Sezer Yamanel R,bozaykut a Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. . 2022; 75 - 79. 10.14744/zkmj.2021.88709
IEEE	taştanoğlu h,Sezer Yamanel R,bozaykut a "Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice." , ss.75 - 79, 2022. 10.14744/zkmj.2021.88709
ISNAD	taştanoğlu, hüseyin vd. "Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice". (2022), 75-79. https://doi.org/10.14744/zkmj.2021.88709

APA	taştanoğlu h, Sezer Yamanel R, bozaykut a (2022). Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. Zeynep Kamil medical journal (Online), 53(2), 75 - 79. 10.14744/zkmj.2021.88709
Chicago	taştanoğlu hüseyin,Sezer Yamanel Rabia Gönül,bozaykut abdulkadir Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. Zeynep Kamil medical journal (Online) 53, no.2 (2022): 75 - 79. 10.14744/zkmj.2021.88709
MLA	taştanoğlu hüseyin,Sezer Yamanel Rabia Gönül,bozaykut abdulkadir Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. Zeynep Kamil medical journal (Online), vol.53, no.2, 2022, ss.75 - 79. 10.14744/zkmj.2021.88709
AMA	taştanoğlu h,Sezer Yamanel R,bozaykut a Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. Zeynep Kamil medical journal (Online). 2022; 53(2): 75 - 79. 10.14744/zkmj.2021.88709
Vancouver	taştanoğlu h,Sezer Yamanel R,bozaykut a Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice. Zeynep Kamil medical journal (Online). 2022; 53(2): 75 - 79. 10.14744/zkmj.2021.88709
IEEE	taştanoğlu h,Sezer Yamanel R,bozaykut a "Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice." Zeynep Kamil medical journal (Online), 53, ss.75 - 79, 2022. 10.14744/zkmj.2021.88709
ISNAD	taştanoğlu, hüseyin vd. "Frequency of glucose-6-phosphate dehydrogenase enzyme deficiency in newborns with prolonged jaundice". Zeynep Kamil medical journal (Online) 53/2 (2022), 75-79. https://doi.org/10.14744/zkmj.2021.88709