Aiming to raise “good physicians” with adequate and distinct qualifications concerning the care, skills, values and behavior with the objective of providing protective, curative and rehabilitative services for society, medical education has had to transition from face-to-face education to distance education due to the COVID-19 pandemic. This transition has brought about the obligation for students who had been trained mostly in the laboratory and clinical settings to pursue online education. Instead of the physical setting in which students are present, distance education brings learning, access to resources and the usage of these resources to the foreground. To this end, the mobile application named “DERS” (class/course in Turkish) developed by the researcher was used as the mobile learning environment for the course titled Infectious Diseases and Clini- cal Microbiology offered in the fourth year. The impact of the mobile learning environment used throughout the course of the study on academic success and mobile learning readiness levels among students was assessed. The study was conducted during the fourth year course titled Infectious Diseases and Clinical Microbiology of 32 hours conducted with 66 medical students; significant diffe- rences in the academic success and mobile learning readiness levels among stu- dents were identified at the end of the study.