Yıl: 2022 Cilt: 33 Sayı: 11 Sayfa Aralığı: 964 - 970 Metin Dili: İngilizce DOI: 10.5152/tjg.2022.21822 İndeks Tarihi: 25-05-2023

Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey

Öz:
Background: The frequency of genotype 4 hepatitis C virus infection is significantly higher in a city compared to other provinces in Turkey. In this study, we aimed to investigate the epidemiology and risk factors of hepatitis C virus genotype 4 infection in Kayseri province of Turkey. Methods: A case–control study was conducted with 61 hepatitis C virus genotype 4-infected patients and 71 controls. A questionnaire was administered to the patients and controls, asking for information about the risk factors of hepatitis C virus transmission. Core/ E1 and NS5B regions of hepatitis C virus genome were amplified and sequenced by Sanger method. Phylogenetic analysis and molecular clock analysis were performed. The risk was determined by calculating the odds ratio and 95% CI. Logistic regression analysis was per- formed to determine the effect of risk factors by controlling for confounding variables. Results: Kayseri isolates were closely related to type 4d sequences but formed a separate cluster. According to the molecular clock analysis, hepatitis C virus genotype 4d entered Kayseri province probably between 1941 and 1988. Blood transfusion and surgical inter- vention were found to be significant risk factors for the infection. Conclusion: Epidemiological data showed that hepatitis C virus genotype 4d infections are significantly associated with unsafe medical procedures.
Anahtar Kelime:

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APA gökahmetoğlu s, Polat C, Atalay M, Can Sezgin G, Ergör G, Aygen B, Gürsoy S, Abacioglu H (2022). Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. , 964 - 970. 10.5152/tjg.2022.21822
Chicago gökahmetoğlu selma,Polat Ceylan,Atalay Mustafa Altay,Can Sezgin Gülten,Ergör Gül,Aygen Bilgehan,Gürsoy Sebnem,Abacioglu Hakan Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. (2022): 964 - 970. 10.5152/tjg.2022.21822
MLA gökahmetoğlu selma,Polat Ceylan,Atalay Mustafa Altay,Can Sezgin Gülten,Ergör Gül,Aygen Bilgehan,Gürsoy Sebnem,Abacioglu Hakan Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. , 2022, ss.964 - 970. 10.5152/tjg.2022.21822
AMA gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. . 2022; 964 - 970. 10.5152/tjg.2022.21822
Vancouver gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. . 2022; 964 - 970. 10.5152/tjg.2022.21822
IEEE gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H "Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey." , ss.964 - 970, 2022. 10.5152/tjg.2022.21822
ISNAD gökahmetoğlu, selma vd. "Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey". (2022), 964-970. https://doi.org/10.5152/tjg.2022.21822
APA gökahmetoğlu s, Polat C, Atalay M, Can Sezgin G, Ergör G, Aygen B, Gürsoy S, Abacioglu H (2022). Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turkish Journal of Gastroenterology, 33(11), 964 - 970. 10.5152/tjg.2022.21822
Chicago gökahmetoğlu selma,Polat Ceylan,Atalay Mustafa Altay,Can Sezgin Gülten,Ergör Gül,Aygen Bilgehan,Gürsoy Sebnem,Abacioglu Hakan Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turkish Journal of Gastroenterology 33, no.11 (2022): 964 - 970. 10.5152/tjg.2022.21822
MLA gökahmetoğlu selma,Polat Ceylan,Atalay Mustafa Altay,Can Sezgin Gülten,Ergör Gül,Aygen Bilgehan,Gürsoy Sebnem,Abacioglu Hakan Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turkish Journal of Gastroenterology, vol.33, no.11, 2022, ss.964 - 970. 10.5152/tjg.2022.21822
AMA gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turkish Journal of Gastroenterology. 2022; 33(11): 964 - 970. 10.5152/tjg.2022.21822
Vancouver gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey. Turkish Journal of Gastroenterology. 2022; 33(11): 964 - 970. 10.5152/tjg.2022.21822
IEEE gökahmetoğlu s,Polat C,Atalay M,Can Sezgin G,Ergör G,Aygen B,Gürsoy S,Abacioglu H "Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey." Turkish Journal of Gastroenterology, 33, ss.964 - 970, 2022. 10.5152/tjg.2022.21822
ISNAD gökahmetoğlu, selma vd. "Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey". Turkish Journal of Gastroenterology 33/11 (2022), 964-970. https://doi.org/10.5152/tjg.2022.21822