The aim of study is to determine the general tendency of the studies on local socioscientific issues (LSSI) within the scope of some parameters such as purpose, method, sample level, data collection tool, data analysis method, topic, and result with a systematic literature review. As a result of scanning international databases such as ERIC, Wiley Online Library Full Collection, Springer LINK, Taylor & Francis, ProQuest Dissertations, Google Scholar, and national databases such as National Thesis Center and ULAKBİM National Database, a total of 35 studies consisting of 31 articles and 4 theses were included in the research. The findings showed that the studies generally aim to examine the effect of LSSI teaching on the development of different variables such as conceptual understanding, critical thinking, and nature of science views. Pre-service teachers, secondary and high school students were used as study group. The questionnaires were generally used as data collection tool and quantitative and qualitative data analyzes are performed at approximately the same rate. The studies mostly focused on environmental-based issues such as global climate change, nuclear power plants, HPPs, river pollution, and biofuel energy sources. Moreover, LSSI had a positive effect on the development of different variables. Based on the findings, it has been recommended to increase the number of studies that examine the relationships between different variables in LSSI teaching.