The present study was to investigate the possibility of the cultivation of P. ostreatus, P. sajor-caju, P. florida were researched. For the propagation of the main culture, 2.0% malt-extract agar was used whereas wheat grains were used for the propagation of spawn, and also clover stalk (C), walnut husk waste (W) and sugar beet pulp (S) were used as culture media. The mycelium growing days, primordial initiation days, harvest periods and yield of P. ostreatus, P. sajor-caju and P. florida grown on different agro-wastes were observed to be 10.3-15.3 days, 22.0-71.3 days, 27.7-80.0 days, 27.3-42.7 g/100 g and 48.0-85.2 %, respectively. In conclusion, we understood that for the growing of Pleurotus spp. the C-S medium is more suitable compared with compost medium in the way of yield.