The aim of this study is to investigate the relationship between the attitudes of the senior students of the Faculty of Theology toward teaching profession and their academic self-efficacy. The study group consists of 209 senior students in the Faculty of Theology at Sinop University. According to the results of the research, while students' attitudes towards teaching profession are quite high, their perceptions of academic self-efficacy are moderate. In addition, there is a positive and statistically significant correlation between students' professional attitudes and academic self-efficacy. (r= 0.26; p = 0.000).There is a statistically significant relationship between the attitude towards teaching profession and the type of secondary education that is graduated, the profession to be done after graduation, and the reason for choosing the faculty. No statistically significant relationship was found between the attitude towards teaching profession and the variables of gender, economic status, place of residence, preparatory reading status and students' averages. Also, no statistically significant difference was found between the students' self-efficacy score and gender, the economic income, the place of residence, the type of secondary education graduated, preparatory reading, the reason for choosing the faculty, the profession required and the grade point average.