Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases

İsaoğulları, Şadi Yenel; topal, uğur; Akyuz, Muhammet; gök, mustafa; ARIKAN, TURKMEN BAHADIR; Sözüer, Erdoğan Mütevelli

doi:10.4274/tjcd.galenos.2020.2020-7-5

Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases

Muhammet AKYÜZ, (Erciyes University Faculty of Medicine, Department of General Surgery, Kayseri, Turkey)

Uğur TOPAL, (Erciyes University Faculty of Medicine, Department of Surgical Oncology, Kayseri, Turkey)

Erdoğan SÖZÜER, (Erciyes University Faculty of Medicine, Department of Surgical Oncology, Kayseri, Turkey)

Şadi Yenel İSAOĞULLARI, (Erciyes University Faculty of Medicine, Department of General Surgery, Kayseri, Turkey)

Mustafa GÖK, (Erciyes University Faculty of Medicine, Department of General Surgery, Kayseri, Turkey)

Türkmen Bahadır ARIKAN (Erciyes University Faculty of Medicine, Department of General Surgery, Kayseri, Turkey)

Türk Kolon ve Rektum Hastalıkları Dergisi

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Yıl: 2021 Cilt: 31 Sayı: 1 Sayfa Aralığı: 65 - 71 Metin Dili: İngilizce DOI: 10.4274/tjcd.galenos.2020.2020-7-5 İndeks Tarihi: 21-05-2022

Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases

Öz:

Aim: We aimed to determine the clinical value of erythrocyte distribution width (RDW) and mean platelet volume (MPV) in the diagnosis of acute appendicitis (AA) and in determining the severity of the disease. Method: Patients who were operated between January 2013 and January 2020 with a preliminary diagnosis of AA were included in the study. The patients were divided into two groups as Group 1 negative appendectomy and Group 2 acute appendicitis. In addition, Group 2 is divided into subgroups as a:perforated and b: non-perforated. RDW and MPV were compared between the groups and subgroups. Results: A total of 861 patients participated in our study. Group 1 consisted of 144 patients and Group 2 consisted of 717 patients. The mean age was similar in both groups (33.02 vs 35.34, p=0.088), female sex was higher in Group 1 (52.8% vs 42.9, p=0.019), RDW was higher in Group 1 (14.03 vs 13.67, p=0.007), MPV was similar between the groups (8.81 vs 8.95, p=0.363). RDW was an independent risk factor in the diagnosis of AA in multivariate analysis (odds ratio 0.604, 95% confidence interval (minimum-maximum) 0.420-0.868, p=0.006). RDW and MPV were independent variables in the diagnosis of perforated appendicitis in multivariate logistic regression analysis. Conclusion: RDW is a useful parameter in the diagnosis of AA and in determining the severity of the disease. However, MPV value does not have sufficient diagnostic value.

Anahtar Kelime:

Akut Apandisit Olgularında Eritrosit Dağılım Genişliği ve Ortalama Trombosit Hacminin Tanıda ve Hastalığın Şiddetini Belirlemedeki Prediktif Değeri

Öz:

Amaç: Eritrosit dağılım genişliğinin (RDW) ve ortalama trombosit hacminin (MPV) akut apandisit tanısındaki ve hastalığın şiddetini belirlemedeki klinik değerini saptamayı amaçladık. Yöntem: Ocak 2013 ile ocak 2020 tarihleri arasında akut appendisit ön tanısı ile opere edilen hastalar çalışmaya dahil edildi. Hastalar Grup 1 negatif appendektomi; Grup 2 akut apandisit olmak üzere iki gruba ayrıldı. Ayrıca Grup 2a: Perfore ve 2b: nonperfore olmak üzere subgruplara ayrıldı. Nötrofil sayısı, RDW ve MPV oranları gruplarda ve subgruplarda karşılaştırıldı. Bulgular: Çalışmamıza 861 hasta dahil edildi. Grup 1: 144, Grup 2: 717 hastadan oluşuyordu. Yaş ortalaması (33,02 vs 35,34 p=0,088) ve MPV oranları (8,81 vs 8,95 p=0,363) açısından her iki grup arasında anlamlı farklılık yoktu. Grup 1’de kadın cinsiyet oranı daha yüksekti (%52,8 vs 42,9 p=0,019). Ayrıca RDW oranları Grup 1’de daha yüksekti (14,03% vs 13,67% p=0,007) ve RDW oranları multivaryant analizde akut appendisit tanısında bağımsız bir göstergeydi (odds ratio: 0,604 %95 confidence interval: (minimum-maksimum) 0,420-0,868 p=0,006). RDW ve MPV oranları çok değişkenli lojistik regresyon analizinde perfore appendisit tanısında bağımsız değişkenlerdi. Sonuç: Akut appendisit tanısında ve hastalığın şiddetinin belirlemesinde RDW yararlı bir parametredir. Fakat MPV değerinin yeterli tanısal değeri yoktur.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Akyuz M, topal u, Sözüer E, İsaoğulları Ş, gök m, ARIKAN T (2021). Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. , 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
Chicago	Akyuz Muhammet,topal uğur,Sözüer Erdoğan Mütevelli,İsaoğulları Şadi Yenel,gök mustafa,ARIKAN TURKMEN BAHADIR Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. (2021): 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
MLA	Akyuz Muhammet,topal uğur,Sözüer Erdoğan Mütevelli,İsaoğulları Şadi Yenel,gök mustafa,ARIKAN TURKMEN BAHADIR Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. , 2021, ss.65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
AMA	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. . 2021; 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
Vancouver	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. . 2021; 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
IEEE	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T "Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases." , ss.65 - 71, 2021. 10.4274/tjcd.galenos.2020.2020-7-5
ISNAD	Akyuz, Muhammet vd. "Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases". (2021), 65-71. https://doi.org/10.4274/tjcd.galenos.2020.2020-7-5

APA	Akyuz M, topal u, Sözüer E, İsaoğulları Ş, gök m, ARIKAN T (2021). Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. Türk Kolon ve Rektum Hastalıkları Dergisi, 31(1), 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
Chicago	Akyuz Muhammet,topal uğur,Sözüer Erdoğan Mütevelli,İsaoğulları Şadi Yenel,gök mustafa,ARIKAN TURKMEN BAHADIR Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. Türk Kolon ve Rektum Hastalıkları Dergisi 31, no.1 (2021): 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
MLA	Akyuz Muhammet,topal uğur,Sözüer Erdoğan Mütevelli,İsaoğulları Şadi Yenel,gök mustafa,ARIKAN TURKMEN BAHADIR Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. Türk Kolon ve Rektum Hastalıkları Dergisi, vol.31, no.1, 2021, ss.65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
AMA	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. Türk Kolon ve Rektum Hastalıkları Dergisi. 2021; 31(1): 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
Vancouver	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases. Türk Kolon ve Rektum Hastalıkları Dergisi. 2021; 31(1): 65 - 71. 10.4274/tjcd.galenos.2020.2020-7-5
IEEE	Akyuz M,topal u,Sözüer E,İsaoğulları Ş,gök m,ARIKAN T "Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases." Türk Kolon ve Rektum Hastalıkları Dergisi, 31, ss.65 - 71, 2021. 10.4274/tjcd.galenos.2020.2020-7-5
ISNAD	Akyuz, Muhammet vd. "Predictive Value of Red Cell Distribution Width and Mean Platelet Volume in the Diagnosis and Determination of Severity in Acute Appendicitis Cases". Türk Kolon ve Rektum Hastalıkları Dergisi 31/1 (2021), 65-71. https://doi.org/10.4274/tjcd.galenos.2020.2020-7-5